Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678079 | 1.00 | CTSK (0.48) | CTSKSLC7A5SLC15A1DPP4DPP8 | |
| SCHEMBL4226580 | 0.93 | CTSK (0.43) | CTSKSLC7A5SLC15A1DPP4DPP8 | |
| SCHEMBL4226584 | 0.93 | CTSK (0.43) | CTSKSLC7A5SLC15A1DPP4DPP8 | |
| SCHEMBL8003112 | 0.91 | CTSK (0.59) | CTSKSLC15A1DPP4DPP8DPP9 | |
| SCHEMBL6031204 | 0.91 | CTSK (0.59) | CTSKSLC15A1DPP4DPP8DPP9 | |
| SCHEMBL9572289 | 0.91 | CTSK (0.59) | CTSKSLC15A1DPP4DPP8DPP9 | |
| SCHEMBL18520339 | 0.87 | DPP8 (0.45) | CTSKSLC15A1DPP4DPP8DPP9 | |
| SCHEMBL8270222 | 0.87 | SLC7A5 (0.42) | CTSKSLC7A5SLC15A1DPP4DPP8 | |
| SCHEMBL8817388 | 0.86 | CAPN1 (0.46) | CTSKSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL2475740 | 0.86 | CAPN1 (0.46) | CTSKSLC7A5ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170325-A2 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009019505-A2 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-12 | — | — | WO | disclosed |