Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226584 | 1.00 | CTSK (0.43) | CTSKCTSSCTSLCTSBCTSC | |
| SCHEMBL3678078 | 0.93 | CTSK (0.48) | CTSKCTSLCTSBSLC7A5SLC15A1 | |
| SCHEMBL3678079 | 0.93 | CTSK (0.48) | CTSKCTSLCTSBSLC7A5SLC15A1 | |
| SCHEMBL4775289 | 0.92 | CTSK (0.53) | CTSKCTSSCTSLCTSBSLC15A1 | |
| SCHEMBL4775282 | 0.92 | CTSK (0.53) | CTSKCTSSCTSLCTSBSLC15A1 | |
| SCHEMBL3326210 | 0.92 | CTSK (0.53) | CTSKCTSSCTSLCTSBSLC15A1 | |
| SCHEMBL3326212 | 0.92 | CTSK (0.53) | CTSKCTSSCTSLCTSBSLC15A1 | |
| SCHEMBL30091429 | 0.90 | CTSK (0.44) | CTSKCTSSCTSLCTSBCTSC | |
| SCHEMBL30091426 | 0.89 | DPP4 (0.46) | CTSKDPP4DPP8DPP9MMP3 | |
| SCHEMBL13039705 | 0.88 | CAPN1 (0.41) | CTSLCTSBSLC7A5PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009152462-A2 | METHOD OF REGULATING CELL GROWTH USING A PROTEASOME INHIBITOR | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-12-17 | — | — | WO | disclosed |