Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706328 | 0.80 | HTT (0.40) | ALDH1A1LMNAMAPTTDP1TSHR | |
| SCHEMBL7758673 | 0.77 | FOLH1 (0.49) | ELANEFOLH1ALDH1A1MAPTTSHR | |
| SCHEMBL4489861 | 0.75 | SLC16A3 (0.40) | FOLH1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL11709541 | 0.72 | CTNNB1 (0.57) | MEN1HPGDKMT2ACTNNB1WNT3A | |
| SCHEMBL3678741 | 0.71 | ABCB1 (0.34) | ABCB1ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL1502390 | 0.71 | ABL1 (0.38) | ELANELMNATDP1POLBNPSR1 | |
| SCHEMBL27880348 | 0.70 | ERCC5 (0.53) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL5520169 | 0.70 | CYP19A1 (0.54) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| SCHEMBL3112839 | 0.70 | L3MBTL1 (0.39) | ALDH1A1LMNAMAPTTDP1MAPK1 | |
| SCHEMBL27962512 | 0.70 | HTT (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261207-A1 | Intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives | Aventisub II Inc. (US) | 2010-12-15 | — | — | EP | disclosed |