Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112839 | 0.75 | L3MBTL1 (0.39) | NPC1CES2CES1HDAC8HDAC1 | |
| SCHEMBL28552412 | 0.75 | CES2 (0.43) | CES2CES1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL11709541 | 0.74 | CTNNB1 (0.57) | NPC1CTNNB1WNT3AL3MBTL1 | |
| SCHEMBL1050668 | 0.74 | CTNNB1 (0.57) | CES2CES1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL29391353 | 0.74 | CTNNB1 (0.57) | CES2CES1CTNNB1WNT3AALDH1A1 | |
| SCHEMBL17278187 | 0.73 | ALDH1A1 (0.50) | CES2CES1HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL11706328 | 0.72 | HTT (0.40) | NPC1HDAC8HDAC1CTNNB1WNT3A | |
| SCHEMBL7026997 | 0.72 | GABRA1 (0.41) | HDAC8HDAC1CTNNB1WNT3AHTT | |
| SCHEMBL11705776 | 0.72 | HCRTR1 (0.55) | ABCB1NPC1HDAC8HDAC1HTT | |
| SCHEMBL27724305 | 0.72 | USP5 (0.46) | NPC1L3MBTL1LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101182306-B | Method for synthesizing intermediate of fexofenadine | UNIV CHONGQING | 2011-04-27 | — | — | CN | disclosed |
| EP-2261207-A1 | Intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives | Aventisub II Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| CN-101182306-A | Method for synthesizing intermediate of fexofenadine | UNIV CHONGQING (CN) | 2008-05-21 | — | — | CN | disclosed |