SCHEMBL3678744

SCHEMBL3678744

CCN1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.43
ELANE P08246 1/20 0.43
CTSG P08311 1/20 0.43
CTRC Q99895 1/20 0.43
CA9 Q16790 3/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA7 P43166 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
GMNN O75496 1/20 0.39
MAPT P10636 1/20 0.39
THPO P40225 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MGLL Q99685 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13578733 0.88 F2 (0.42) F2ELANECTSGCTRCCA9
SCHEMBL12748857 0.82 ALDH1A1 (0.38) F2ELANECTSGCTRCCA9
SCHEMBL1901728 0.81 CA9 (0.45) CA9CA1CA2CA7CA12
SCHEMBL13590980 0.81 ALDH1A1 (0.37) F2ELANECTSGCTRCCA9
SCHEMBL12163243 0.79 CA1 (0.46) CA9CA1CA2CA7CA12
SCHEMBL1813132 0.79 CA1 (0.50) CA9CA1CA2CA7CA12
SCHEMBL4449615 0.78 CA1 (0.42) CA9CA1CA2CA7CA12
SCHEMBL12235615 0.76 LMNA (0.51) F2ELANECTSGCTRCALDH1A1
SCHEMBL14341825 0.76 CA9 (0.38) CA9CA1CA2CA7CA12
SCHEMBL844833 0.76 BLM (0.54) F2ELANECTSGCTRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10272654-B2 Polycarbonate composition having improved flame resistance for extrusion applications COVESTRO DEUTSCHLAND AG (DE) 2019-04-30 US disclosed
CN-101842429-B Flame retardant polycarbonate comprising a polyol BAYER MATERIALSCIENCE AG 2013-03-27 CN disclosed
US-20120244359-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED FLAME RESISTANCE FOR EXTRUSION APPLICATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
CN-101842429-A Flame retardant polycarbonate comprising a polyol BAYER MATERIALSCIENCE AG 2010-09-22 CN disclosed
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
US-20090137709-A1 POLYOL-CONTAINING, FLAME-RESISTANT POLYCARBONATES, PROCESSES FOR PREPARING THE SAME AND PRODUCTS CONTAINING THE SAME BAYER MATERIALSCIENCE AG (DE) 2009-05-28 US disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
US-5668201-A Flame retardant graft copolymer composition GENERAL ELECTRIC COMPANY (US) 1997-09-16 US disclosed
US-5326800-A Use of salts in combination with halogenated phthalimides for flameproof finishing of glass fibre-containing polycarbonate moulded members BAYER AKTIENGESELLSCHAFT (DE) 1994-07-05 US disclosed
US-4769493-A Process for producing tetrafluorophthalic acid SDS BIOTECH K.K. (JP) 1988-09-06 US disclosed
EP-0259663-A1 Process for producing tetrafluorophihalic acid SDS Biotech K.K. (JP) 1988-03-16 EP disclosed
EP-0219014-A2 Flame retardant elastomeric compositions GENERAL ELECTRIC COMPANY (US) 1987-04-22 EP disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0042561-B1 FIRE-PROOFED MOULDING MASSES BASED ON AROMATIC THERMOPLASTIC POLYESTERS, PROCESS FOR ITS PREPARATION AND USE IN THE PRODUCTION OF SHAPED ARTICLES BAYER AG (DE) 1985-03-27 EP disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed