SCHEMBL3679167

SCHEMBL3679167

CCCCOC(C)(OCC)c1ccc(C(=O)O)c(C(=O)O)c1C(C)(OCC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPK1 P28482 3/20 0.36
CYP3A4 P08684 3/20 0.36
TP53 P04637 2/20 0.35
LMNA P02545 3/20 0.34
ESR1 P03372 2/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP2D6 P10635 1/20 0.34
NR1H2 P55055 1/20 0.34
RNASEL Q05823 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17797784 0.91 TSHR (0.32) TSHRALDH1A1HSD17B10CYP3A4LMNA
SCHEMBL3677295 0.90 TSHR (0.38) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL17797798 0.85 TSHR (0.41) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL5450242 0.82
SCHEMBL17800909 0.80 TSHR (0.32) TSHRALDH1A1HSD17B10CYP3A4LMNA
SCHEMBL17797861 0.80 TSHR (0.32) TSHRALDH1A1HSD17B10CYP3A4LMNA
SCHEMBL3374028 0.79 TSHR (0.45) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL17798480 0.76 RARB (0.34) TSHRTDP1L3MBTL1ALDH1A1TP53
SCHEMBL17797912 0.74 TSHR (0.38) TSHRTDP1ALDH1A1HSD17B10CYP3A4
SCHEMBL10392099 0.73 ALOX15 (0.39) TSHRTDP1ALDH1A1HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421531-B1 NITRILE COPOLYMER RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2020-10-07 EP disclosed
US-10793704-B2 Nitrile copolymer rubber composition, cross-link rubber composition, and cross-linked rubber ZEON CORPORATION (JP) 2020-10-06 US disclosed
US-10266628-B2 Nitrile copolymer rubber composition ZEON CORPORATION (JP) 2019-04-23 US disclosed
US-20190040237-A1 NITRILE COPOLYMER RUBBER COMPOSITION, CROSS-LINKABLE RUBBER COMPOSITION, AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2019-02-07 US disclosed
EP-3421531-A1 NITRILE COPOLYMER RUBBER COMPOSITION, CROSSLINKABLE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2019-01-02 EP disclosed
US-9926445-B2 Nitrile copolymer rubber composition ZEON CORPORATION (JP) 2018-03-27 US disclosed
EP-2937382-B1 NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORP (JP) 2017-10-25 EP disclosed
US-20170101498-A1 NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORPORATION (JP) 2017-04-13 US disclosed
US-9587086-B2 Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties EASTMAN CHEMICAL COMPANY (US) 2017-03-07 US disclosed
EP-3124532-A1 NITRILE COPOLYMER RUBBER COMPOSITION Zeon Corporation (JP) 2017-02-01 EP disclosed
US-20140100315-A1 NITRILE COPOLYMER LATEX COMPOSITION AND NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORPORATION (JP) 2014-04-10 US disclosed
US-8648137-B2 Nitrile copolymer latex composition and nitrile copolymer rubber composition ZEON CORPORATION (JP) 2014-02-11 US disclosed
US-8563644-B2 Nitrile copolymer rubber composition and nitrile copolymer latex composition ZEON CORPORATION (JP) 2013-10-22 US disclosed
US-20100330319-A1 NITRILE COPOLYMER LATEX COMPOSITION AND NITRILE COPOLYMER RUBBER COMPOSITION ZEON CORPORATION (JP) 2010-12-30 US disclosed
US-20100104789-A1 NITRILE COPOLYMER RUBBER COMPOSITION AND NITRILE COPOLYMER LATEX COMPOSITION ZEON CORPORATION (JP) 2010-04-29 US disclosed
EP-0340618-B1 Organic composition containing a fluoroalkyl sulfonic acid salt DOW CHEMICAL CO (US) 1996-02-28 EP disclosed
EP-0191845-B1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1990-11-07 EP disclosed
EP-0340618-A1 Organic composition containing a fluoroalkyl sulfonic acid salt THE DOW CHEMICAL COMPANY (US) 1989-11-08 EP disclosed
US-4806571-A ANTISTATIC AGENTS THE DOW CHEMICAL COMPANY (US) 1989-02-21 US disclosed
US-4618630-A ESPECIALLY FOR POLYURETHANE FOAM PRODUCTION THE DOW CHEMICAL CO. (US) 1986-10-21 US disclosed