SCHEMBL3374028

SCHEMBL3374028

CCCCOC(C)(OCCCC)c1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
TP53 P04637 1/20 0.41
PTPN11 Q06124 2/20 0.40
LMNA P02545 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.39
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
PLK1 P53350 1/20 0.38
SLC37A4 O43826 1/20 0.37
PPARA Q07869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10392099 0.85 ALOX15 (0.39) TSHRTDP1ALDH1A1HSD17B10MAPK1
SCHEMBL7876590 0.82 SLC37A4 (0.36) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL11889790 0.82 TSHR (0.38) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL3679167 0.79 TSHR (0.38) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL3677295 0.79 TSHR (0.38) TSHRTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL8906262 0.79 BID (0.43) ALDH1A1HSD17B10PTPN11KDM4ECA12
SCHEMBL20853637 0.78 CA12 (0.40) TSHRALDH1A1KDM4EMEN1RECQL
SCHEMBL3100646 0.77 CA12 (0.43) TSHRTDP1ALDH1A1HSD17B10CYP3A4
SCHEMBL26622690 0.77 BID (0.44) ALDH1A1HSD17B10PTPN11KDM4EPLK1
SCHEMBL6152073 0.77 BID (0.44) ALDH1A1HSD17B10PTPN11KDM4EPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539031-B2 Plastisol compositions AVECIA LTD (GB) 2001-01-31 EP claimed
US-5795695-A PHOTO-QUALITY RECORDING XEROX CORPORATION (US) 1998-08-18 US claimed
EP-0539031-B1 Plastisol compositions ZENECA LTD (GB) 1996-11-27 EP claimed
EP-0470040-B1 Process for the preparation of a rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-09-11 EP claimed
EP-0470042-B1 Process for the preparation of a masterbatch rubber having polymer bound functionality GOODYEAR TIRE & RUBBER (US) 1996-05-08 EP claimed
EP-0502141-A4 PRINTABLE PAPER COATING COMPOSITION 1992-11-19 EP claimed
EP-0502141-A1 PRINTABLE PAPER COATING COMPOSITION BASF CORPORATION (US) 1992-09-09 EP claimed
WO-1992003288-A1 PRINTABLE PAPER COATING COMPOSITION BASF CORPORATION (US) 1992-03-05 WO claimed
EP-0075486-B1 PROCESS FOR PREPARING CURABLE MIXTURES POLYSAR LIMITED (CA) 1988-08-17 EP claimed
CN-110087876-B Asymmetric laminates including asymmetric multilayer interlayers 首诺公司 2022-07-22 CN disclosed
CN-110087877-B Acoustical panel with high interlayer thickness factor 首诺公司 2022-03-04 CN disclosed
CN-109789674-B Sound-damping multilayer laminate 首诺公司 2021-09-03 CN disclosed
CN-107090265-B Re-peelable adhesive and surface protective film 东洋油墨SC控股株式会社 2021-03-12 CN disclosed
EP-3559072-B1 THERMOPLASTIC POLYURETHANE WITH HIGH RESISTANCE TO FURTHER TEARING BASF SE (DE) 2021-02-17 EP disclosed
WO-1992003288-A1 PRINTABLE PAPER COATING COMPOSITION BASF CORPORATION (US) 1992-03-05 WO disclosed
EP-0121864-A2 Nonwoven products having low residual free formaldehyde content AIR PRODUCTS AND CHEMICALS, INC. (US) 1984-10-17 EP disclosed
US-4449978-A TETRAPOLYMER OF VINYL ACETATE, ETHYLENE, N-METHYLOLACRYLAMIDE, AND ACRYLAMIDE AIR PRODUCTS AND CHEMICALS, INC. (US) 1984-05-22 US disclosed
US-4419283-A AT LEAST THREE MUTUALLY IMMISCIBLE LIQUID PHASES SCHNEIDER RONALD A 1983-12-06 US disclosed
EP-0035669-A2 Aqueous dispersions and process for making them BAYER AG (DE) 1981-09-16 EP disclosed
US-4210567-A Plastisol of an acrylate polymer and a plasticizer TEROSON G.M.B.H. (DE) 1980-07-01 US disclosed