Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600695 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10TDP1VCAM1 | |
| SCHEMBL7745871 | 0.79 | TSHR (0.43) | ALDH1A1TSHRHSD17B10TDP1VCAM1 | |
| SCHEMBL19906429 | 0.76 | TDP1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL5792188 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1VCAM1 | |
| SCHEMBL1614538 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1VCAM1 | |
| SCHEMBL1614543 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1VCAM1 | |
| SCHEMBL8655017 | 0.72 | — | — | |
| Oxalic Acid SCHEMBL28234215 | 0.72 | ALDH1A1 (0.77) | ALDH1A1TSHRHSD17B10TDP1FFAR3 | |
| Hydrogen Peroxide SCHEMBL15610564 | 0.71 | — | — | |
| Hydrogen Peroxide SCHEMBL28219767 | 0.71 | TSHR (0.91) | ALDH1A1TSHRHSD17B10TDP1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141145-B1 | Efficient and highly enantioselective Rh-catalyzed hydrogenations of unsaturated lactate precursors with chiral bisphospholanes as ligands | THYSSENKRUPP UHDE GMBH (DE) | 2013-02-20 | — | — | EP | disclosed |
| WO-2010000354-A1 | EFFICIENT AND HIGHLY ENANTIOSELECTIVE RH-CATALYZED HYDROGENATIONS OF UNSATURATED LACTACTE PRECURSORS WITH CHIRAL BISPHOSPHOLANES AS LIGANDS | UHDE GMBH (DE) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141145-A1 | Efficient and highly enantioselective Rh-catalyzed hydrogenations of unsaturated lactate precursors with chiral bisphospholanes as ligands | Uhde GmbH (DE) | 2010-01-06 | — | — | EP | disclosed |
| US-4124608-A | Preparation of 2-oxoalkanoic acids | TEXACO INC. (US) | 1978-11-07 | — | — | US | disclosed |