SCHEMBL7745871

SCHEMBL7745871

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nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
VCAM1 P19320 1/20 0.37
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 2/20 0.31
ATM Q13315 1/20 0.31
HTT P42858 1/20 0.31
NR4A1 P22736 1/20 0.31
NR4A2 P43354 1/20 0.31
NR4A3 Q92570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27928189 0.79 ALDH1A1 (0.41) TSHRALDH1A1HSD17B10TDP1
SCHEMBL3679186 0.79 ALDH1A1 (0.47) TSHRALDH1A1VCAM1HSD17B10TDP1
SCHEMBL11600695 0.79 ALDH1A1 (0.47) TSHRALDH1A1VCAM1HSD17B10TDP1
SCHEMBL8460934 0.76 MGAM (0.43) TSHRALDH1A1KDM4EATM
SCHEMBL8460939 0.76 MGAM (0.43) TSHRALDH1A1KDM4EATM
SCHEMBL23829890 0.74 ALDH1A1 (0.47) TSHRALDH1A1HSD17B10TDP1KDM4E
SCHEMBL6229866 0.74 ALDH1A1 (0.47) TSHRALDH1A1HSD17B10TDP1KDM4E
SCHEMBL542268 0.74 HCAR2 (0.40) TSHRALDH1A1KDM4E
SCHEMBL542266 0.74 HCAR2 (0.40) TSHRALDH1A1KDM4E
SCHEMBL542267 0.74 HCAR2 (0.40) TSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001038461-A1 COMPOSITION THE ASSOCIATED OCTEL COMPANY LIMITED (GB) 2001-05-31 WO disclosed