SCHEMBL3679355

SCHEMBL3679355

Cc1cc(-c2ccc(O)cc2C)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.67
ESR1 P03372 7/20 0.67
TLR8 Q9NR97 2/20 0.58
HSD17B1 P14061 4/20 0.56
HSD17B2 P37059 3/20 0.56
FGFR1 P11362 1/20 0.51
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
TNIK Q9UKE5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736132 1.00 ESR2 (0.67) ESR2ESR1TLR8HSD17B1HSD17B2
SCHEMBL14760397 0.92 HSD17B1 (0.61) ESR2ESR1TLR8HSD17B1HSD17B2
SCHEMBL12660789 0.86 ESR2 (0.69) ESR2ESR1TLR8HSD17B1FGFR1
SCHEMBL17753396 0.86 TLR8 (0.60) ESR2ESR1TLR8HSD17B1HSD17B2
SCHEMBL29738442 0.83 ESR2 (0.76) ESR2ESR1HSD17B1FGFR1
Methylhydroquinone SCHEMBL5712106 0.83 HSD17B1 (0.64) ESR2ESR1TLR8HSD17B1HSD17B2
SCHEMBL439874 0.83 ESR2 (0.76) ESR2ESR1HSD17B1FGFR1
Methylhydroquinone SCHEMBL10426478 0.82 TP53 (0.62) ESR2ESR1TLR8HSD17B1HSD17B2
Methylhydroquinone SCHEMBL29364957 0.82
Methylhydroquinone SCHEMBL36349 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100036029-A1 POLYMER-(ORGANO)CLAY COMPOSITE, COMPOSITION COMPRISING THE COMPOSITE, SHEET-LIKE MATERIAL COMPRISING THE COMPOSITE OR THE COMPOSITION, AND PROCESS FOR PRODUCTION OF POLYMER-(ORGANO)CLAY COMPOSITE ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-02-11 US disclosed
EP-2113526-A1 POLYMER-(ORGANO)CLAY COMPLEX, COMPOSITION COMPRISING THE COMPLEX, SHEET-LIKE MATERIAL COMPRISING THE COMPLEX OR COMPOSITION, AND METHOD FOR PRODUCTION OF POLYMER-(ORGANO)CLAY COMPLEX Asahi Kasei Chemicals Corporation (JP) 2009-11-04 EP disclosed
EP-0884342-B1 Resin for coating formation and method for producing the same UNITIKA LTD (JP) 2003-09-24 EP disclosed
US-5902872-A POLYARYLATE COMPRISING 2,2-BIS/3-METHYL-4-HYDROXYPHENYL/PROPANE UNITS, TEREPHTHALIC ACID UNITS AND ISOPHTHALIC ACID UNITS, HAVING SPECIFIED INHERENT VISCOSITY UNITIKA, LTD. (JP) 1999-05-11 US disclosed
EP-0884342-A1 Resin for coating formation and method for producing the same UNITIKA LTD. (JP) 1998-12-16 EP disclosed