SCHEMBL14760397

SCHEMBL14760397

Cc1cc(-c2ccc(O)c(C)c2)ccc1O.Cc1cc(O)ccc1-c1ccc(O)cc1C

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 7/20 0.61
HSD17B2 P37059 6/20 0.61
ESR2 Q92731 9/20 0.56
ESR1 P03372 7/20 0.56
TLR8 Q9NR97 2/20 0.54
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C19 P33261 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6736132 0.92 ESR2 (0.67) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL3679355 0.92 ESR2 (0.67) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL29379733 0.83 HSD17B1 (0.70) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL29429122 0.83 HSD17B1 (0.70) HSD17B1HSD17B2ESR2ESR1TLR8
Methylhydroquinone SCHEMBL5712106 0.83 HSD17B1 (0.64) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL2399731 0.83 HSD17B1 (0.70) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL503208 0.83 HSD17B1 (0.70) HSD17B1HSD17B2ESR2ESR1TLR8
SCHEMBL503213 0.82 ESR2 (0.74) HSD17B1ESR2ESR1CYP3A4
SCHEMBL272034 0.82 HSD17B1 (0.68) HSD17B1HSD17B2ESR2ESR1CYP3A4
Methylhydroquinone SCHEMBL10426478 0.82 TP53 (0.62) HSD17B1HSD17B2ESR2ESR1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277936-B1 Method of preparing polycarbonate resin LG CHEMICAL LTD (KR) 2013-03-13 EP disclosed