Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296846 | 0.92 | KMT2A (0.41) | ALDH1A1KMT2AHSD17B10MEN1NR3C1 | |
| SCHEMBL2297280 | 0.85 | LMNA (0.47) | ALDH1A1HSD17B10PPARGPPARDPPARA | |
| SCHEMBL2292040 | 0.82 | NPC1 (0.49) | ALDH1A1KMT2AHSD17B10MEN1POLB | |
| SCHEMBL2292814 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2AHSD17B10MEN1LMNA | |
| SCHEMBL2297393 | 0.79 | LMNA (0.52) | ALDH1A1KMT2AHSD17B10MEN1POLB | |
| SCHEMBL2295296 | 0.79 | NAMPT (0.48) | NAMPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2294367 | 0.78 | KMT2A (0.46) | ALDH1A1KMT2AHSD17B10MEN1LMNA | |
| SCHEMBL2296022 | 0.77 | KMT2A (0.45) | ALDH1A1KMT2AHSD17B10MEN1LMNA | |
| SCHEMBL2293920 | 0.77 | NAMPT (0.51) | NAMPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2292597 | 0.77 | KMT2A (0.46) | ALDH1A1KMT2AHSD17B10MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164326-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | Euro-Celtique, S.A. (LU) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |