SCHEMBL3679744

SCHEMBL3679744

Cc1ccc(C(=O)Nc2cccc3ccccc23)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.76
NPC1 O15118 6/20 0.76
CYP1A2 P05177 2/20 0.76
CYP3A4 P08684 2/20 0.76
CYP2D6 P10635 2/20 0.76
CYP2C19 P33261 2/20 0.76
CYP2C9 P11712 1/20 0.76
KMT2A Q03164 3/20 0.71
PARP1 P09874 1/20 0.62
EGFR P00533 1/20 0.59
ERBB2 P04626 1/20 0.59
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 2/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
GAA P10253 2/20 0.58
MEN1 O00255 1/20 0.58
TP53 P04637 1/20 0.58
NFKB1 P19838 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30735621 1.00 RAB9A (0.76) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL4629282 0.87 RAB9A (0.58) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL26885232 0.87 NPC1 (0.81) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL30184438 0.86 NPC1 (1.00) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL4642544 0.86 NPC1 (1.00) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL14859447 0.86 RAB9A (0.71) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL3659724 0.85 RAB9A (0.84) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL7539037 0.85 NPC1 (0.78) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL18773847 0.84 KMT2A (0.77) RAB9ANPC1CYP1A2CYP3A4CYP2D6
SCHEMBL29124091 0.84 NPC1 (0.76) RAB9ANPC1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229483-A Amide potassium complex for catalyzing lactide ring-opening polymerization and preparation method thereof 北京服装学院 2023-12-15 CN claimed
CN-117229483-A Amide potassium complex for catalyzing lactide ring-opening polymerization and preparation method thereof 北京服装学院 2023-12-15 CN disclosed
US-8647528-B2 Water absorbing agent and production method thereof NIPPON SHOKUBAI CO., LTD. (JP) 2014-02-11 US disclosed
US-20100270501-A1 Water absorbing agent and production method thereof NIPPON SHOKUBAI CO., LTD. (JP) 2010-10-28 US disclosed