Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588574 | 0.89 | CA2 (0.59) | CA2ACESMN1; SMN2NPC1TP53 | |
| SCHEMBL7971423 | 0.89 | CA2 (0.59) | CA2ACESMN1; SMN2NPC1TP53 | |
| SCHEMBL6850655 | 0.89 | CA2 (0.59) | CA2ACESMN1; SMN2NPC1TP53 | |
| SCHEMBL6938746 | 0.89 | CA2 (0.59) | CA2ACESMN1; SMN2NPC1TP53 | |
| SCHEMBL349308 | 0.86 | ITGB3 (0.58) | SMN1; SMN2ITGB3ITGA2PKMALOX5 | |
| SCHEMBL349307 | 0.86 | ITGB3 (0.58) | SMN1; SMN2ITGB3ITGA2PKMALOX5 | |
| SCHEMBL350064 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2PKMALOX5HTT | |
| SCHEMBL350063 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2PKMALOX5HTT | |
| SCHEMBL347285 | 0.83 | ITGB3 (0.42) | CA2ACEITGB3ITGA2MAPK1 | |
| SCHEMBL10796469 | 0.80 | HTT (0.51) | SMN1; SMN2NPC1TP53RAB9AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252393-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | Evonik Degussa GmbH (DE) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009112325-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2009-09-17 | — | — | WO | disclosed |