Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.90 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.90 |
| ▸ | MAPT | P10636 | 1/20 | 0.90 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.90 |
| ▸ | BLM | P54132 | 1/20 | 0.90 |
| ▸ | MGLL | Q99685 | 1/20 | 0.90 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.90 |
| ▸ | CES1 | P23141 | 7/20 | 0.90 |
| ▸ | CES2 | O00748 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | F7 | P08709 | 3/20 | 0.65 |
| ▸ | F3 | P13726 | 3/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | PPARD | Q03181 | 2/20 | 0.65 |
| ▸ | PPARA | Q07869 | 2/20 | 0.65 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679976 | 1.00 | FAAH (0.90) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL22195368 | 0.98 | FAAH (0.88) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL459980 | 0.98 | FAAH (0.93) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL459981 | 0.98 | FAAH (0.93) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| Arachidonyl Trifluoromethylketone SCHEMBL9880640 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| Arachidonyl Trifluoromethylketone SCHEMBL30426991 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL24938531 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL8059738 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL24938529 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A | |
| SCHEMBL4085373 | 0.95 | FAAH (1.00) | FAAHALDH1A1PLA2G4BMAPTPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-7470807-B2 | Suppress production of both prostaglandins and leukotrienes and have reduced side effects; treatment of various inflammatory diseases, autoimmune diseases, allergic diseases, pain and fibrosis; for example, methyl 3-[3-acetylamino-4-cyclopentyloxy-5-(naphthalen-2-yl)phenyl]propionate | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | FAAH 102/4885ALDH1A1 996/4885PLA2G4B 526/4885 |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | FAAH 102/4885ALDH1A1 996/4885PLA2G4B 526/4885 |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | FAAH 102/4885ALDH1A1 996/4885PLA2G4B 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.