SCHEMBL3680013

SCHEMBL3680013

CCCCC=CC1C(C(=O)OCC)C1(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
FAAH O00519 2/20 0.39
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PTGS2 P35354 1/20 0.36
PDE4D Q08499 1/20 0.36
MAPT P10636 1/20 0.35
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MGLL Q99685 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680011 1.00 LMNA (0.58) LMNAFAAHNR1I2PGRADORA3
SCHEMBL11160230 0.94 LMNA (0.55) LMNAFAAHPGRADORA3MAPT
SCHEMBL11160225 0.94 LMNA (0.55) LMNAFAAHPGRADORA3MAPT
SCHEMBL2167340 0.86 LMNA (0.41) LMNATSHRALDH1A1F7F3
SCHEMBL2167334 0.86 LMNA (0.41) LMNATSHRALDH1A1F7F3
SCHEMBL2168058 0.86 LMNA (0.41) LMNATSHRALDH1A1F7F3
SCHEMBL15977318 0.82 LMNA (0.38) LMNAFAAHPGRADORA3PDE4D
SCHEMBL3678023 0.80 F7 (0.42) LMNAFAAHPGRADORA3MAPT
SCHEMBL3678027 0.80 F7 (0.42) LMNAFAAHPGRADORA3MAPT
SCHEMBL15977303 0.80 F7 (0.38) LMNAFAAHPGRADORA3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1934063-B Method for producing (2-formyl-1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
US-7700799-B2 Method for producing (2-formyl-1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2009-05-28 US disclosed
US-7498459-B2 Method for producing (1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-03 US disclosed
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-23 US disclosed
CN-1934063-A Method for producing (2-formyl-1-alkenyl)cyclopropane compound SUMITOMO CHEMICAL CO (JP) 2007-03-21 CN disclosed
EP-1728781-A1 PROCESS FOR PRODUCTION OF (1-ALKENYL)CYCLOPROPANES Sumitomo Chemical Company, Limited (JP) 2006-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137839-A1 METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND ACSL3, ACSL1, ARL1 LMNA 2696/4885FAAH 41/4885NR1I2 1128/4885
US-20070197818-A1 Method for producing (1-alkenyl) cyclopropane compound ACSL3, ARL1, ACSL1 LMNA 3763/4885FAAH 434/4885NR1I2 1974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.