SCHEMBL3680122

SCHEMBL3680122

OC=CCCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 17/20 0.55
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11879387 0.89 GPR52 (0.57) GPR52
SCHEMBL2243799 0.86 HDAC3 (0.47) GPR52CA1CA2TDP1
SCHEMBL9399999 0.86 HDAC3 (0.47) GPR52CA1CA2TDP1
SCHEMBL7762166 0.85 GPR52 (0.57) GPR52TDP1
SCHEMBL7762164 0.85 GPR52 (0.57) GPR52TDP1
SCHEMBL9715286 0.85 GPR52 (0.57) GPR52TDP1
SCHEMBL3930495 0.85 TRPV1 (0.50) CA1CA2
SCHEMBL1799318 0.80 TDP1 (0.52) GPR52CA1CA2TDP1
SCHEMBL8554597 0.79 TDP1 (0.58) GPR52TDP1
SCHEMBL13078847 0.79 GPR52 (0.53) GPR52TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016120890-A1 AN ENANTIOSELECTIVE PROCESS FOR THE SYNTHESIS OF (2S,4R)-4-HYDROXYPIPECOLIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-08-04 WO claimed
WO-2016120890-A1 AN ENANTIOSELECTIVE PROCESS FOR THE SYNTHESIS OF (2S,4R)-4-HYDROXYPIPECOLIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-08-04 WO disclosed
CN-1850503-B Multilayer rubber slice for hot pressing conjugation SHINETSU CHEMICAL CO 2010-05-26 CN disclosed
US-7718723-B2 Curable fluoropolyether rubber compositions and rubber articles SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-05-18 US disclosed
EP-1715005-B1 Curable fluoropolyether rubber compositions and rubber articles SHINETSU CHEMICAL CO (JP) 2009-08-05 EP disclosed
EP-1422260-B1 Curable fluoropolyether rubber compositions and rubber articles SHINETSU CHEMICAL CO (JP) 2008-12-31 EP disclosed
US-7449540-B2 Curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-11-11 US disclosed
US-20070225433-A1 Curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. 2007-09-27 US disclosed
EP-1837375-A2 Curable silicone composition Shin-Etsu Chemical Co., Ltd. (JP) 2007-09-26 EP disclosed
US-20070073025-A1 Curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. 2007-03-29 US disclosed
EP-0215347-B1 PROCESS FOR THE PREPARATION OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE-2,2-DIOXIDE AS WELL AS FOR ITS PURIFICATION HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-24 EP disclosed
EP-0218076-B1 PROCESS FOR THE PREPARATION OF THE NON-TOXIC SALTS OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ON-2,2-DIOXIDE HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-03 EP disclosed
EP-0173082-B1 PROCESS FOR THE PREPARATION OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE-2,2-DIOXIDE AND ITS NON-TOXIC SALTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-31 EP disclosed
EP-0159516-B1 METHOD FOR THE PREPARATION OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE-2,2-DIOXIDE AND ITS NON-TOXIC SALTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-01-20 EP disclosed
EP-0218076-A1 Process for the preparation of the non-toxic salts of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxide HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-15 EP disclosed
EP-0217024-A1 Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-on-2,2-dioxide HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-08 EP disclosed
EP-0215347-A1 Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide as well as for its purification HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-25 EP disclosed
EP-0173082-A1 Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and its non-toxic salts HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-05 EP disclosed
EP-0159516-A1 Method for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and its non-toxic salts HOECHST AKTIENGESELLSCHAFT (DE) 1985-10-30 EP disclosed
EP-0155634-A2 Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and of its non-toxic salts, as well as of acetoacetamide-N-sulfonic acid occurring as an intermediary in this process, and its salts HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-25 EP disclosed