Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715286 | 1.00 | GPR52 (0.57) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL7762166 | 1.00 | GPR52 (0.57) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL28679572 | 0.90 | MAOB (0.71) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL433496 | 0.90 | MAOB (0.71) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL18595441 | 0.90 | MAOB (0.71) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL11387571 | 0.88 | TDP1 (0.58) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL7855313 | 0.88 | GPR52 (0.53) | GPR52ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL6761553 | 0.88 | TDP1 (0.52) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL97473 | 0.88 | GPR52 (0.48) | GPR52MAOBALDH1A1HPGDALOX15 | |
| SCHEMBL19031848 | 0.88 | GPR52 (0.48) | GPR52MAOBALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070217-A1 | DNA-CLEAVING ANTITUMOR AGENTS | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-09-27 | — | — | WO | disclosed |