Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680780 | 0.88 | CYP2C19 (0.36) | CYP2C19POLBBLMATM | |
| SCHEMBL4971701 | 0.85 | HDAC3 (0.36) | CYP2C19POLBBLMATMLMNA | |
| SCHEMBL28345659 | 0.85 | HDAC3 (0.36) | CYP2C19POLBBLMATMLMNA | |
| SCHEMBL29488604 | 0.82 | CYP2C19 (0.32) | CYP2C19POLBBLMATM | |
| SCHEMBL29488592 | 0.82 | CYP2C19 (0.32) | CYP2C19POLBBLMATM | |
| SCHEMBL19640265 | 0.82 | CYP2C19 (0.38) | CYP2C19POLBBLMATMALDH1A1 | |
| SCHEMBL4457981 | 0.82 | TDP1 (0.31) | TDP1 | |
| SCHEMBL11752721 | 0.81 | THRB (0.31) | — | |
| SCHEMBL20995515 | 0.81 | CES2 (0.36) | CYP2C19POLBBLMATMHSD17B10 | |
| SCHEMBL29629354 | 0.81 | CES2 (0.36) | CYP2C19POLBBLMATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220363873-A1 | SILANE COUPLING AGENT COMPOSITION COMPRISING SILANE COMPOUND AND PROTEIN MODIFYING AGENT, AND RUBBER COMPOSITION COMPRISING THE SAME | ENEOS CORPORATION (JP) | 2022-11-17 | — | — | US | claimed |
| EP-3981610-A1 | SILANE COUPLING AGENT COMPOSITION CONTAINING SILANE COMPOUND AND PROTEIN DENATURING AGENT, AND RUBBER COMPOSITION CONTAINING SAID COMPOSITION | ENEOS Corporation (JP) | 2022-04-13 | — | — | EP | claimed |
| CN-113924335-A | Silane coupling agent composition comprising silane compound and protein denaturing agent, and rubber composition comprising same | 引能仕株式会社 | 2022-01-11 | — | — | CN | claimed |
| CN-113795499-A | Process for producing alkoxysilyl group-containing thiocarboxylic ester | 迈图高新材料公司 | 2021-12-14 | — | — | CN | claimed |
| EP-2681272-B1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-07-08 | — | — | EP | claimed |
| EP-2681272-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2014-01-08 | — | — | EP | claimed |
| WO-2012118918-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-07 | — | — | WO | claimed |
| US-20120225231-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS, INC (US) | 2012-09-06 | — | — | US | claimed |
| US-7847000-B2 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2010-12-07 | — | — | US | claimed |
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |
| CN-100422192-C | Method for producing blocked mercaptosilanes | GEN ELECTRIC (US) | 2008-10-01 | — | — | CN | claimed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | claimed |
| JP-2007509209-A | — | — | 2007-04-12 | — | — | JP | claimed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | claimed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | claimed |
| CN-1784412-A | Method for producing blocked mercaptosilanes | GEN ELECTRIC (US) | 2006-06-07 | — | — | CN | claimed |
| CN-1247687-C | Mineral filled elastomeric compositions | CROMPTON CORP (US) | 2006-03-29 | — | — | CN | claimed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | claimed |
| CN-1481419-A | Mineral filled elastomeric compositions | ��³�նٹ�˾ | 2004-03-10 | — | — | CN | claimed |
| EP-4514889-B1 | STABILIZED COMPOSITIONS OF SULFUR SILANES WITH HIGH MERCAPTO CONTENT | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2026-05-27 | — | — | EP | disclosed |
| US-20250257193-A1 | STABILIZED COMPOSITIONS OF SULFUR SILANES WITH HIGH MERCAPTO CONTENT | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2025-08-14 | — | — | US | disclosed |
| EP-4514889-A1 | STABILIZED COMPOSITIONS OF SULFUR SILANES WITH HIGH MERCAPTO CONTENT | Momentive Performance Materials GmbH (DE) | 2025-03-05 | — | — | EP | disclosed |
| CN-119095904-A | Stable composition of sulfur silanes with high mercapto content | 迈图高新材料有限责任公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-118055862-A | Silica reinforced rubber compositions and articles made therefrom | 迈图高新材料公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117413012-A | Silane coupling agent composition and rubber composition containing same | 引能仕株式会社 | 2024-01-16 | — | — | CN | disclosed |
| WO-2023208772-A1 | STABILIZED COMPOSITIONS OF SULFUR SILANES WITH HIGH MERCAPTO CONTENT | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2023-11-02 | — | — | WO | disclosed |
| US-20230106817-A1 | SILICA-REINFORCED RUBBER COMPOSITIONS AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2023-04-06 | — | — | US | disclosed |
| US-20220363873-A1 | SILANE COUPLING AGENT COMPOSITION COMPRISING SILANE COMPOUND AND PROTEIN MODIFYING AGENT, AND RUBBER COMPOSITION COMPRISING THE SAME | ENEOS CORPORATION (JP) | 2022-11-17 | — | — | US | disclosed |
| EP-3981610-A1 | SILANE COUPLING AGENT COMPOSITION CONTAINING SILANE COMPOUND AND PROTEIN DENATURING AGENT, AND RUBBER COMPOSITION CONTAINING SAID COMPOSITION | ENEOS Corporation (JP) | 2022-04-13 | — | — | EP | disclosed |
| CN-113924335-A | Silane coupling agent composition comprising silane compound and protein denaturing agent, and rubber composition comprising same | 引能仕株式会社 | 2022-01-11 | — | — | CN | disclosed |
| US-10246581-B2 | Rubber compositions containing whey protein | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2019-04-02 | — | — | US | disclosed |
| US-20170342253-A1 | RUBBER COMPOSITIONS CONTAINING WHEY PROTEIN | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2017-11-30 | — | — | US | disclosed |
| US-9447262-B2 | Rubber composition containing blocked mercaptosilanes and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-09-20 | — | — | US | disclosed |
| CN-105452261-A | Continuous process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MAT INC | 2016-03-30 | — | — | CN | disclosed |
| EP-2681272-B1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-07-08 | — | — | EP | disclosed |
| CN-103534305-B | Rubber composition containing blocked mercaptosilanes and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2015-06-24 | — | — | CN | disclosed |
| EP-1270581-B1 | Blocked mercaptosilane coupling agents for filled rubbers | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-02-19 | — | — | EP | disclosed |
| EP-2681272-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2014-01-08 | — | — | EP | disclosed |
| CN-101880415-B | Silica-rubber mixtures having improved hardness | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-05-22 | — | — | CN | disclosed |
| WO-2012118918-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-09-07 | — | — | WO | disclosed |
| US-20120225231-A1 | RUBBER COMPOSITION CONTAINING BLOCKED MERCAPTOSILANES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS, INC (US) | 2012-09-06 | — | — | US | disclosed |
| CN-1681876-B | Silica-rubber mixtures with improved hardness | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-05-30 | — | — | CN | disclosed |
| US-7847000-B2 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2010-12-07 | — | — | US | disclosed |
| CN-101880415-A | Has the silica-rubber mixtures that improves hardness | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-10 | — | — | CN | disclosed |
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | disclosed |
| EP-0958298-B2 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-10-22 | — | — | EP | disclosed |
| US-20080242771-A1 | Butyl Rubber Composition for Tire Treads | LANXESS INC. (CA) | 2008-10-02 | — | — | US | disclosed |
| CN-100422192-C | Method for producing blocked mercaptosilanes | GEN ELECTRIC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-100376585-C | Blocked mercaptosilane coupling agents for filled rubbers | WHITAKER CORP (US) | 2008-03-26 | — | — | CN | disclosed |
| CN-101139355-A | Blocked mercaptosilane coupling agents for filled rubbers | CROMPTON CORP (US) | 2008-03-12 | — | — | CN | disclosed |
| EP-1680469-A4 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2007-09-05 | — | — | EP | disclosed |
| CN-1318520-C | Chemically treated fillers and polymer compositions containing same | PPG IND OHIO INC (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1318519-C | Chemically modified fillers and polymer compositions containing same | PPG IND OHIO INC (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1312229-C | Process for producing chemically treated fillers | PPG IND OHIO INC (US) | 2007-04-25 | — | — | CN | disclosed |
| CN-1312228-C | Process for producing chemically modified fillers | PPG IND OHIO INC (US) | 2007-04-25 | — | — | CN | disclosed |
| US-20070083011-A1 | Blocked mercaptosilane coupling agents for filled rubbers | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-04-12 | — | — | US | disclosed |
| CN-1894329-A | Butyl rubber composition for tire treads | LANXESS INC (CA) | 2007-01-10 | — | — | CN | disclosed |
| US-20060293423-A1 | Silica-filled elastomeric compounds | LANXESS INC. (CA) | 2006-12-28 | — | — | US | disclosed |
| US-7122590-B2 | Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers | GENERAL ELECTRIC COMPANY (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1694764-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | Lanxess Inc. (CA) | 2006-08-30 | — | — | EP | disclosed |
| US-20060183866-A1 | Blocked mercaptosilane coupling agents for filled rubbers | MOMENTIVE PERFORMANCE MATERIALS INC. | 2006-08-17 | — | — | US | disclosed |
| US-7081500-B2 | Mixing a rubber, an inorganic filler, and a blocked mercaptosilane , mixing into the rubber mixture of deblocking agent to deblock the blocked mercaptosilane, and a curing agent; andallowing the rubber mixture to cure | GENERAL ELECTRIC COMPANY (US) | 2006-07-25 | — | — | US | disclosed |
| EP-1680469-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | Lanxess Inc. (CA) | 2006-07-19 | — | — | EP | disclosed |
| US-7078551-B2 | Acylthio propylenesilane compounds; no odor, coupling with rubber and inorganic fillers; for use in tires, shoe soles | GENERAL ELECTRIC COMPANY (US) | 2006-07-18 | — | — | US | disclosed |
| EP-1679315-A1 | Blocked mercaptosilane coupling agents for filled rubbers | GENERAL ELECTRIC COMPANY (US) | 2006-07-12 | — | — | EP | disclosed |
| US-7074876-B2 | Sulfur silane coupling agents which are latent | GENERAL ELECTRIC COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| CN-1261494-C | Silane modified biopoymerized oxidized or silicide stuffing and its production process and use | DEGUSSA (DE) | 2006-06-28 | — | — | CN | disclosed |
| CN-1784412-A | Method for producing blocked mercaptosilanes | GEN ELECTRIC (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1247687-C | Mineral filled elastomeric compositions | CROMPTON CORP (US) | 2006-03-29 | — | — | CN | disclosed |
| US-20060014870-A1 | Blending a rubber, an inorganic filler, and an acylthio propylenesilane compounds, coupling with rubber and inorganic fillers, deblocking the silane compound and curing the rubber; no odor, for use in tires, shoe soles | WITCO CORPORATION | 2006-01-19 | — | — | US | disclosed |
| CN-1681876-A | Silica-rubber mixtures with improved hardness | GEN ELECTRIC (US) | 2005-10-12 | — | — | CN | disclosed |
| WO-2005056664-A1 | BUTYL RUBBER COMPOSITION FOR TIRE TREADS | LANXESS INC. (CA) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005040272-A1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC. (CA) | 2005-05-06 | — | — | WO | disclosed |
| US-20040210001-A1 | Acylthio propylenesilane compounds; no odor, coupling with rubber and inorganic fillers; for use in tires, shoe soles | MOMENTIVE PERFORMANCE MATERIALS INC. | 2004-10-21 | — | — | US | disclosed |
| CN-1481419-A | Mineral filled elastomeric compositions | ��³�նٹ�˾ | 2004-03-10 | — | — | CN | disclosed |
| US-6683135-B2 | FOR USE IN TIRES, SHOE SOLES | MOMENTIVE PERFORMANCE MATERIALS INC. | 2004-01-27 | — | — | US | disclosed |
| US-20030225195-A1 | Silicon compounds such as 2-triethoxysilyl-1-ethylthioacetate, used as binders of rubbers such as butadiene-styrene copolymers, containing fillers | CROMPTON CORPORATION | 2003-12-04 | — | — | US | disclosed |
| US-6608125-B2 | 2-triethoxysilyl-1-ethyl thioacetate; tires | CROMPTON CORPORATION | 2003-08-19 | — | — | US | disclosed |
| EP-0958298-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | CROMPTON CORP (US) | 2003-05-07 | — | — | EP | disclosed |
| US-6528673-B2 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | CROMPTON CORPORATION | 2003-03-04 | — | — | US | disclosed |
| EP-1270581-A2 | Blocked mercaptosilane coupling agents for filled rubbers | CROMPTON CORPORATION (US) | 2003-01-02 | — | — | EP | disclosed |
| CN-1384136-A | Silane modified biopoymerized oxidized or silicide stuffing and its production process and use | DEGUSSA (DE) | 2002-12-11 | — | — | CN | disclosed |
| CN-1376184-A | Chemically modified fillers and polymer compositions containing same | PPG IND OHIO INC (US) | 2002-10-23 | — | — | CN | disclosed |
| CN-1376185-A | Chemically treated fillers and polymer compositions containing same | PPG IND OHIO INC (US) | 2002-10-23 | — | — | CN | disclosed |
| CN-1374988-A | Process for producing chemically modified fillers | PPG IND OHIO INC (US) | 2002-10-16 | — | — | CN | disclosed |
| CN-1374989-A | Process for producing chemically treated fillers | PPG IND OHIO INC (US) | 2002-10-16 | — | — | CN | disclosed |
| US-20020099118-A1 | For use in tires, shoe soles | WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE | 2002-07-25 | — | — | US | disclosed |
| US-6414061-B1 | CURABLE MIXTURE | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| US-20020055646-A1 | Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification | WITCO CORPORATION | 2002-05-09 | — | — | US | disclosed |
| US-20020055568-A1 | 3-(acylmercapto)propyltrialkoxy- or trihydroxysilane | WITCO CORPORATION | 2002-05-09 | — | — | US | disclosed |
| US-20020055564-A1 | Sulfur silane coupling agents which are latent | WITCO CORPORATION | 2002-05-09 | — | — | US | disclosed |
| CN-1242774-A | Blocked mercaptosilane coupling agents for filled rubbers | WHITAKER CORP (US) | 2000-01-26 | — | — | CN | disclosed |
| EP-0958298-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | WITCO CORPORATION (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999009036-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | OSI SPECIALTIES, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1999009036-A1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | OSI SPECIALTIES, INC. (US) | 1999-02-25 | — | — | WO | disclosed |