Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3543497 | 0.71 | HSD11B1 (0.47) | HSD11B1EPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL11152235 | 0.66 | HSD11B1 (0.40) | HSD11B1EPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL16241618 | 0.63 | HPGD (0.46) | HSD11B1GBA1 | |
| SCHEMBL15659952 | 0.60 | CHRM2 (0.43) | HSD11B1EPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL9115414 | 0.60 | HSD11B1 (0.42) | HSD11B1GBA1 | |
| SCHEMBL4357593 | 0.60 | CALM1 (0.45) | GBA1 | |
| SCHEMBL19798405 | 0.59 | EPHX2 (0.50) | HSD11B1EPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL13397148 | 0.59 | SMN1; SMN2 (0.67) | HSD11B1EPHX2CXCR3 | |
| SCHEMBL21327803 | 0.59 | CHRM2 (0.42) | HSD11B1EPHX2CHRM2CHRM4CHRM5 | |
| SCHEMBL726031 | 0.59 | CHRM2 (0.42) | HSD11B1EPHX2CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167232-A1 | A PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | Lucite International UK Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009010782-A1 | A PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2009-01-22 | — | — | WO | disclosed |