Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065935 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL7756952 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL6957299 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL14034743 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL9269275 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL25168671 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL7634664 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL6960220 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL9065483 | 0.84 | TSHR (0.59) | TSHRLTA4HPLA2G4BSMPD1NR5A1 | |
| SCHEMBL14732479 | 0.83 | NR5A1 (0.50) | TSHRLTA4HPLA2G4BNR5A1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | TSHR 4316/4885LTA4H 2655/4885PLA2G4B 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.