Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756952 | 1.00 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL9065935 | 1.00 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL9269275 | 1.00 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL9065483 | 1.00 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL7282207 | 0.98 | TSHR (0.57) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL3029634 | 0.93 | LTA4H (0.53) | TSHRPLA2G4BSMPD1LTA4HTHRB | |
| SCHEMBL910595 | 0.88 | KMT2A (0.54) | TSHRPLA2G4BLTA4H | |
| SCHEMBL6957299 | 0.84 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HTHRA | |
| SCHEMBL3680649 | 0.84 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HGGPS1 | |
| SCHEMBL6960220 | 0.84 | TSHR (0.59) | TSHRPLA2G4BSMPD1LTA4HTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5521185-A | CARBOSYTRIL DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0638311-A1 | REJECTION INHIBITOR FOR TRANSPLANTS AND IL-1 PRODUCTION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |