Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665839 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL3673155 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL6012839 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL14118625 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL617140 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL7275105 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL17678369 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL12510924 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL8433089 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR | |
| SCHEMBL11328260 | 1.00 | KDM4E (0.48) | KDM4EANPEPERAP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10112889-B2 | Continuous process for producing a surfactant in a tube reactor | CLARIANT INTERNATIONAL LTD. (CH) | 2018-10-30 | — | — | US | disclosed |
| US-20170305838-A1 | Continuous Process For Producing A Surfactant In A Tube Reactor | CLARIANT INTERNATIONAL LTD. (CH) | 2017-10-26 | — | — | US | disclosed |
| CN-102850204-B | A kind of method for splitting of (S)-2-aryl propionic non-steroid antiphlogistic | XUZHOU MEDICAL COLLEGE (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-104478703-A | Preparation method of dextrorotatory flurbiprofen | TAICANG YUNTONG BIOCHEMICAL ENGINEERING CO LTD | 2015-04-01 | — | — | CN | disclosed |
| CN-104447283-A | Preparation method for dextro-flurbiprofen | TAICANG YUNTONG BIOCHEMICAL ENGINEERING CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-102408313-B | Preparation method of R-3-butyne-2-alochol | ZHEJIANG APELOA KANGYU PHARMACEUTICAL CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102850204-A | Resolution method of (S)-2-arylpropionic acid non-steroidal anti-inflammatory drug | XUZHOU MEDICAL COLLEGE | 2013-01-02 | — | — | CN | disclosed |
| CN-101928214-B | Method for synthesizing dexketoprofen trometamol | HUANGSHI SHIXING PHARMACEUTICAL CO LTD | 2012-12-19 | — | — | CN | disclosed |
| US-20120157560-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XL TERRA, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| CN-101928214-A | Method for synthesizing dexketoprofen trometamol | HUANGSHI SHIXING PHARMACEUTICAL CO LTD | 2010-12-29 | — | — | CN | disclosed |
| WO-2010138842-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | XLTERRA, INC. (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20100234228-A1 | NOVEL SURFACTANTS AND FORMULATIONS | MONSANTO TECHNOLOGY LLC (US) | 2010-09-16 | — | — | US | disclosed |
| CN-101514156-A | Method for recycling naproxen resolution solvent, resolving agent and by-product by overgravitational field | ZHEJIANG CHARIOTEER PHARMACEUT (CN) | 2009-08-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136070-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | KHK, HKDC1, HK2 | KDM4E 442/4885ANPEP 3699/4885ERAP2 2457/4885 |
| US-20100234228-A1 | NOVEL SURFACTANTS AND FORMULATIONS | PHOSPHO1, GNMT, DDT | KDM4E 825/4885ANPEP 548/4885ERAP2 2412/4885 |
| US-20170305838-A1 | Continuous Process For Producing A Surfactant In A Tube Reactor | FASN, TECR, TERT | KDM4E 4058/4885ANPEP 3837/4885ERAP2 4742/4885 |
| US-20120157560-A1 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF | KHK, HKDC1, HK2 | KDM4E 442/4885ANPEP 3699/4885ERAP2 2457/4885 |
| US-10112889-B2 | Continuous process for producing a surfactant in a tube reactor | FASN, TECR, TERT | KDM4E 4058/4885ANPEP 3837/4885ERAP2 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.