SCHEMBL3680994

SCHEMBL3680994

CC(N)c1ccccc1S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
NFKB1 P19838 1/20 0.46
PNMT P11086 1/20 0.46
LMNA P02545 4/20 0.45
ALDH1A1 P00352 2/20 0.45
GLA P06280 1/20 0.45
HIF1A Q16665 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2C P18825 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37
SLC6A2 P23975 3/20 0.36
TAAR1 Q96RJ0 2/20 0.36
MAOA P21397 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14035785 1.00 CYP2D6 (0.46) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL2782006 0.83 CYP2D6 (0.54) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL14395925 0.83 CYP2D6 (0.54) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL30678522 0.83 CYP2D6 (0.54) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL30678523 0.83 CYP2D6 (0.54) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL17448132 0.83 CYP2D6 (0.54) CYP2D6CYP1A2CYP3A4NFKB1PNMT
Hydrochloric Acid SCHEMBL4696712 0.80 LMNA (0.56) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL3671138 0.78 TSHR (0.39) CYP2D6CYP1A2CYP3A4NFKB1PNMT
SCHEMBL191352 0.78 GABRA1 (0.52) CYP1A2CYP3A4LMNAALDH1A1HIF1A
SCHEMBL29986709 0.78 GABRA1 (0.52) CYP1A2CYP3A4LMNAALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305651-A1 2,3,6-trisubstituted-4-pyrimidone derivatives Mitsubishi Tanabe Pharma Corporation (JP) 2011-04-06 EP disclosed
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed
US-6500842-B1 N-((4-CHLOROPHENYL)METHYL)-8-HYDROXY-7-QUINOLINECARBOXAMIDE ADMINISTERED AS VIRICIDES AGAINST HERPES VIRUS PHARMACIA & UPJOHN COMPANY 2002-12-31 US disclosed
US-6310211-B1 ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 PHARMACIA & UPJOHN COMPANY 2001-10-30 US disclosed
US-6252080-B1 HERPES, CYTOMEGALO VIRUS PHARMACIA & UPJOHN COMPANY 2001-06-26 US disclosed
US-6211376-B1 HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS PHARMACIA & UPJOHN COMPANY 2001-04-03 US disclosed
EP-0927164-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1999-07-07 EP disclosed
WO-1998011073-A1 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 1998-03-19 WO disclosed
US-4592960-A Production of polyolefin copolymer TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-06-03 US disclosed
US-4242474-A A POLYHYDROXY ACRYLIC ESTER REACTED WITH AN ISOCYANATE TERMINATED POLYOXYALKYLENE GLYCOL; BIOPOLYMERS TERUMO CORPORATION (JP) 1980-12-30 US disclosed
US-4064136-A FROM A NITRILE, AN ALCOHOL AND ORTHO-SUBSTITUTED AROMATIC AMINE CIBA-GEIGY AG (CH) 1977-12-20 US disclosed