SCHEMBL3681093

SCHEMBL3681093

NC(=O)CC[C@H](N)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.48
ALOX15 P16050 1/20 0.48
PMP22 Q01453 1/20 0.48
KMT2A Q03164 1/20 0.48
PTGS1 P23219 1/20 0.48
GSTK1 Q9Y2Q3 1/20 0.48
DPP4 P27487 2/20 0.47
DPP8 Q6V1X1 2/20 0.47
DPP9 Q86TI2 2/20 0.47
GLO1 Q04760 1/20 0.42
PTPN1 P18031 1/20 0.40
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
PTGS2 P35354 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483653 0.93 BLM (0.55) BLMALOX15PMP22KMT2APTGS1
SCHEMBL2483655 0.93 BLM (0.55) BLMALOX15PMP22KMT2APTGS1
SCHEMBL8505286 0.93 BLM (0.55) BLMALOX15PMP22KMT2APTGS1
SCHEMBL30481166 0.90 PTGS1 (0.50) BLMPTGS1GSTK1DPP4DPP8
SCHEMBL3681082 0.90 PTGS1 (0.50) BLMPTGS1GSTK1DPP4DPP8
SCHEMBL3681089 0.90 PTGS1 (0.50) BLMPTGS1GSTK1DPP4DPP8
SCHEMBL16203683 0.86 PTGS1 (0.56) PTGS1GSTK1DPP4DPP8DPP9
SCHEMBL30685329 0.84 DPP4 (0.50) BLMALOX15PMP22KMT2APTGS1
SCHEMBL619330 0.83 ALDH1A1 (0.40) BLMKMT2APTGS1GSTK1GLO1
SCHEMBL8346127 0.83 ALDH1A1 (0.40) BLMKMT2APTGS1GSTK1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8333712-B2 Body fluid sampling device CANON KABUSHIKI KAISHA (JP) 2012-12-18 US disclosed
US-20100099122-A1 FERRIC REDUCTASE ACTIVITY OF HISTOPLASMA CAPSULATUM Y-GLUTAMYLTRANSFERASE WISCONSIN ALUMNI RESEARCH FOUNDATION 2010-04-22 US disclosed
US-20070161926-A1 BODY FLUID SAMPLING DEVICE CANON KABUSHIKI KAISHA (JP) 2007-07-12 US disclosed
EP-0392021-B1 METHOD FOR ANALYZING COMPONENTS KYOWA MEDEX CO LTD (JP) 1994-09-14 EP disclosed
US-5302513-A Quantitative analysis KYOWA MEDEX CO., LTD. (JP) 1994-04-12 US disclosed
EP-0392021-A1 METHOD FOR ANALYZING COMPONENTS KYOWA MEDEX CO. LTD. (JP) 1990-10-17 EP disclosed
EP-0147430-A1 METHOD AND COMPOSITION FOR DETERMINATION OF GAMMA GLUTAMYL TRANSPEPTIDASE COULTER ELECTRONICS INC. (US) 1985-07-10 EP disclosed
WO-1984004931-A1 METHOD AND COMPOSITION FOR DETERMINATION OF GAMMA GLUTAMYL TRANSPEPTIDASE COULTER ELECTRONICS (US) 1984-12-20 WO disclosed
EP-0018628-A1 Method of determining gamma-glutamyl transpeptidase BEHRINGWERKE Aktiengesellschaft (DE) 1980-11-12 EP disclosed
US-4049702-A DIAGNOSIS OF LIVER DISEASE BY DETERMINATION OF G-GLUTAMYL-TRANS-PEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-09-20 US disclosed
US-3979447-A DETERMINATION OF G-GLUTAMYLTRANSPEPTIDASE BOEHRINGER MANNHEIM G.M.B.H. (DT) 1976-09-07 US disclosed