Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483653 | 1.00 | BLM (0.55) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL2483655 | 1.00 | BLM (0.55) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL3681093 | 0.93 | BLM (0.48) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL7541728 | 0.88 | BLM (0.54) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL7541733 | 0.88 | BLM (0.54) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL6119573 | 0.88 | GRM8 (0.56) | BLMPTGS1GSTK1DPP4DPP8 | |
| SCHEMBL6045489 | 0.88 | GRM8 (0.56) | BLMPTGS1GSTK1DPP4DPP8 | |
| SCHEMBL8505283 | 0.88 | GRM8 (0.56) | BLMPTGS1GSTK1DPP4DPP8 | |
| SCHEMBL14359927 | 0.85 | DPP4 (0.55) | BLMALOX15PMP22KMT2APTGS1 | |
| SCHEMBL6064968 | 0.85 | ALOX15 (0.44) | BLMALOX15PMP22KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988007851-A1 | LIPOSOME ENTRAPPED N-METHYL-D-ASPARTATE RECEPTOR BLOCKERS | INNOVATIVE THERAPEUTICS CORPORATION (US) | 1988-10-20 | — | — | WO | claimed |
| US-5945509-A | A POLYPEPTIDE THAT CODES FOR A MEMBRANE PROTEIN INVOLVED IN NEUROTRANSMISSION; THERAPY AND DIAGNOSIS OF NERVOUS SYSTEMDISORDERS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-08-31 | — | — | US | disclosed |
| US-5739291-A | MONOCLONAL ANTIBODY BINDS TO GENETIC ENGINEERED PROTEIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-04-14 | — | — | US | disclosed |
| US-5202257-A | Pure DNA which is capable of hybridizing with receptor polynucleotides under mild conditions | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1993-04-13 | — | — | US | disclosed |
| WO-1988007851-A1 | LIPOSOME ENTRAPPED N-METHYL-D-ASPARTATE RECEPTOR BLOCKERS | INNOVATIVE THERAPEUTICS CORPORATION (US) | 1988-10-20 | — | — | WO | disclosed |