Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.83 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.83 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172629 | 1.00 | PTGER4 (0.83) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3681349 | 1.00 | PTGER4 (0.83) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10210272 | 0.92 | PTGER4 (0.70) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10210364 | 0.91 | PTGER4 (0.71) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10210123 | 0.91 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6165091 | 0.91 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6165089 | 0.91 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL10210267 | 0.89 | PTGER4 (0.71) | PTGER4 | |
| SCHEMBL10210279 | 0.89 | PTGER4 (0.76) | PTGER4 | |
| SCHEMBL10210255 | 0.89 | PTGER4 (0.84) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234337-A1 | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-25 | — | — | US | claimed |
| US-20080021021-A1 | Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | claimed |
| EP-1782830-A1 | PREVENTIVE AND/OR REMEDY FOR LOWER URINARY TRACT DISEASES CONTAINING EP4 AGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-09 | — | — | EP | claimed |
| US-7858610-B2 | Preventive and/or remedy for lower urinary tract diseases containing EP4 agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20080234337-A1 | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20080021021-A1 | Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1782830-A1 | PREVENTIVE AND/OR REMEDY FOR LOWER URINARY TRACT DISEASES CONTAINING EP4 AGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1782829-A1 | PREVENTIVE AND/OR REMEDY FOR HYPERKALEMIA CONTAINING EP4 AGONIST | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234337-A1 | Preventive and/or Remedy for Hyperkalemia Containing Ep4 Agonist | KCNJ4, KCNK4, KCNA4 | PTGER4 86/4885PTGER3 297/4885PTGER2 333/4885 |
| US-20080021021-A1 | Preventive And/Or Remedy For Lower Urinary Tract Diseases Containing Ep4 Agonist | PTGER4, PTGES3, CYSLTR1 | PTGER4 1/4885PTGER3 4/4885PTGER2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.