SCHEMBL3681422

SCHEMBL3681422

C[Si](C)(C)n1ccc(N=O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682057 0.73
SCHEMBL9390665 0.68
SCHEMBL21893016 0.68 DYRK1A (0.37)
SCHEMBL21287886 0.60 BCHE (0.36)
SCHEMBL15879552 0.60 CRBN (0.33)
SCHEMBL18007365 0.58 POLB (0.30)
SCHEMBL3677466 0.56
SCHEMBL3681890 0.56
SCHEMBL11706620 0.55
Hydrochloric Acid SCHEMBL11707885 0.53 ADRA2A (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US claimed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US claimed
US-8188195-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2012-05-29 US claimed
US-20100168378-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-01 US claimed
US-9670299-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2017-06-06 US disclosed
US-20160032030-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2016-02-04 US disclosed
US-9127100-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2015-09-08 US disclosed
US-20140100340-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2014-04-10 US disclosed
US-8623967-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2014-01-07 US disclosed
US-20130096264-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-04-18 US disclosed
US-8188195-B2 Polymers functionalized with nitroso compounds BRIDGESTONE CORPORATION (JP) 2012-05-29 US disclosed
US-20100168378-A1 POLYMERS FUNCTIONALIZED WITH NITROSO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-01 US disclosed