SCHEMBL15879552

SCHEMBL15879552

Cn1ccc(N=O)nc1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
BRD9 Q9H8M2 2/20 0.32
BRD4 O60885 1/20 0.32
TAF1 P21675 1/20 0.32
BRPF1 P55201 1/20 0.32
CREBBP Q92793 1/20 0.32
CECR2 Q9BXF3 1/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CB P42338 1/20 0.32
PIK3CG P48736 1/20 0.32
KDM4E B2RXH2 2/20 0.31
KDM6A O15550 1/20 0.31
KDM4A O75164 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KDM5C P41229 1/20 0.31
KDM2B Q8NHM5 1/20 0.31
DOHH Q9BU89 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439647 0.71
SCHEMBL31227892 0.70
SCHEMBL27952255 0.70 PIK3CB (0.41) CRBNBRD9BRD4TAF1BRPF1
SCHEMBL20611026 0.70
SCHEMBL23128404 0.70
SCHEMBL25428969 0.70
SCHEMBL11250319 0.70
Iodide SCHEMBL29172953 0.68 PIK3CB (0.40) CRBNBRD9BRD4TAF1BRPF1
SCHEMBL3682057 0.67
SCHEMBL15360079 0.67 SMPD3 (0.44) CRBNBRD9BRD4TAF1BRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385100-B2 Compositions and methods for recognition of RNA using triple helix forming peptide nucleic acids The Research Foundation for the State University o (US) 2019-08-20 US disclosed
US-10260089-B2 Compositions and methods for recognition of RNA using triple helical peptide nucleic acids THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 2019-04-16 US disclosed
US-20170009280-A1 COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS UNIV NEW YORK STATE RES FOUND (US) 2017-01-12 US disclosed
US-20140206838-A1 COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2014-07-24 US disclosed
CN-1506494-A Non-electrolytic goldplating liquid �ض���ѧ��ʽ���� 2004-06-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170009280-A1 COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS TARBP1, TRDMT1, ADAR CRBN 4159/4885BRD9 1095/4885BRD4 2901/4885
US-10260089-B2 Compositions and methods for recognition of RNA using triple helical peptide nucleic acids TARBP1, TRDMT1, ADAR CRBN 4159/4885BRD9 1095/4885BRD4 2901/4885
US-10385100-B2 Compositions and methods for recognition of RNA using triple helix forming peptide nucleic acids TARBP1, TRDMT1, NSUN3 CRBN 4224/4885BRD9 1110/4885BRD4 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.