SCHEMBL3682009

SCHEMBL3682009

CC1(C(=O)Cl)CC(C)(C(=O)Cl)CC(C)(C(=O)Cl)C1

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.38
PKM P14618 1/20 0.32
GAA P10253 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932523 0.80
SCHEMBL9876428 0.78
SCHEMBL15304230 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL2279732 0.75
SCHEMBL1938094 0.75
SCHEMBL4633004 0.74 FFAR3 (0.37) FFAR3PKMGAAALDH1A1TSHR
SCHEMBL9956420 0.73
SCHEMBL246831 0.73 ALDH1A1 (0.42) FFAR3ALDH1A1
SCHEMBL16609955 0.73 ALDH1A1 (0.42) FFAR3ALDH1A1
SCHEMBL16609936 0.73 ALDH1A1 (0.42) FFAR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817362-B1 Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers NOVARTIS AG (CH) 2010-09-22 EP claimed
US-20070244211-A1 Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers NOVARTIS AG (CH) 2007-10-18 US claimed