Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686915 | 1.00 | MAOB (0.46) | MAOBPTPN1MAPTALDH1A1NPC1 | |
| SCHEMBL3690295 | 0.88 | MAPT (0.60) | PTPN1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3682208 | 0.88 | LMNA (0.50) | MAOBPTPN1MAPTALDH1A1NPC1 | |
| SCHEMBL3695219 | 0.86 | PDE4A (0.59) | MAOBPTPN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5915550 | 0.84 | MAOB (0.47) | MAOBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5915541 | 0.84 | MAOB (0.47) | MAOBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4854910 | 0.82 | MAPT (0.49) | MAOBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4849955 | 0.82 | MAPT (0.49) | MAOBMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3696884 | 0.82 | MAOB (0.60) | MAOBMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5915793 | 0.82 | MAOB (0.49) | MAOBMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |