Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459046 | 0.83 | NAAA (0.48) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL28460620 | 0.83 | NAAA (0.48) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL28458189 | 0.83 | NAAA (0.48) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL28458122 | 0.83 | NAAA (0.48) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL28447183 | 0.83 | NAAA (0.48) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL25271571 | 0.79 | CA12 (0.43) | DNM1ALDH1A1NAAADGKAFAAH | |
| SCHEMBL28450536 | 0.78 | ALDH1A1 (0.47) | DNM1ALDH1A1NAAALMNAATM | |
| SCHEMBL25276950 | 0.78 | CA12 (0.45) | DNM1NAAADGKAFAAHMEN1 | |
| SCHEMBL25227673 | 0.78 | CA12 (0.45) | DNM1NAAADGKAFAAHMEN1 | |
| SCHEMBL25276942 | 0.78 | CA12 (0.45) | DNM1NAAADGKAFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809726-B1 | USE OF 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS | LANXESS SOLUTIONS US INC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-1833951-B1 | DITHIOCARBAMYL ß-HYDROXY FATTY ACID ESTERS AS ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORP (US) | 2012-08-22 | — | — | EP | disclosed |
| US-8097731-B2 | Reaction products of mercaptobenzothiazoles, mercaptothiazolines, and mercaptobenzimidalzoles with epoxides as lubricant additives | CROMPTON CORPORATION (US) | 2012-01-17 | — | — | US | disclosed |
| US-8048832-B2 | 1,3 dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| EP-2314661-A1 | Lubricant and fuel compositions containing hydroxy polycarboxylic acid esters | Chemtura Corporation (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-1654342-B1 | REACTION PRODUCTS OF MERCAPTOBENZOTHIAZOLES, MERCAPTOTHIAZOLINES, AND MERCAPTOBENZIMIDAZOLES WITH EPOXIDES AS LUBRICANT ADDITIVES | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7696136-B2 | Lubricant compositions containing hydroxy carboxylic acid and hydroxy polycarboxylic acid esters | CROMPTON CORPORATION (US) | 2010-04-13 | — | — | US | disclosed |
| US-20090181870-A1 | 1,3 DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-7541319-B2 | 1,3-dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| US-7521401-B2 | Dithiocarbamyl β-hydroxy fatty acid esters as additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-04-21 | — | — | US | disclosed |
| WO-2001036572-A1 | SUBSTITUTED LINEAR THIOUREA COMPOUNDS AS ADDITIVES FOR LUBRICANTS | CROMPTON CORPORATION (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6187722-B1 | Imidazole thione additives for lubricants | UNIROYAL CHEMICAL COMPANY, INC. | 2001-02-13 | — | — | US | disclosed |
| US-6187726-B1 | ALKYL ETHER OR SULFIDE SIDE CHAIN THAT ENABLES THE ADDITIVE TO BE SOLUBLE IN FULLY FORMULATED CRANKCASE OIL BASED ON MINERAL AND GROUP II, III, AND IV BASE OILS | CK WITCO CORPORATION | 2001-02-13 | — | — | US | disclosed |
| WO-2001007543-A1 | IMIDAZOLE THIONE ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000053703-A1 | CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-09-14 | — | — | WO | disclosed |
| US-5935913-A | EXTREME PRESSURE LUBRICANTS; ASHLESS AND NONPHOSPHORUS, ANTIWEAR, ANTIFATIGUE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0039818-A1 | Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |