Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.62 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.51 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12860221 | 1.00 | CA2 (0.62) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL12860453 | 1.00 | CA2 (0.62) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL6518229 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL5049747 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| Hydrochloric Acid SCHEMBL28630937 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL25279786 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL3671861 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL3682871 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL5046728 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 | |
| SCHEMBL2334605 | 0.98 | CA2 (0.60) | CA2CA1MAPK1CPB2ZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112154145-B | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2023-10-17 | — | — | CN | claimed |
| CN-110944992-B | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-109996792-B | Heterocyclic compounds having activity as modulators of muscarinic M1 and/or M4 receptors in the treatment of CNS diseases and pain | 赫普泰雅治疗有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-110903306-B | Muscarinic receptor agonists | 赫普泰雅治疗有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-109851610-B | Bicyclic aza compounds as muscarinic M1 and/or M4 receptor agonists | 赫普泰雅治疗有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-108025004-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-108290055-B | Oxime compounds as agonists of the muscle M1 and/or M4 receptor | 赫普泰雅治疗有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-112154145-A | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2020-12-29 | — | — | CN | claimed |
| CN-107406449-B | Spiro compounds as agonists of the muscarinic M1 receptor and/or M4 receptor | 赫普泰雅治疗有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-110944992-A | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-109851610-A | Azabicyclo compound as muscarine M1 and/or M4 receptor stimulating agent | 赫普泰雅治疗有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-106458986-B | Bicyclic aza compounds as muscarinic M1 and/or M4 receptor agonists | 赫普泰雅治疗有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-107406449-A | As muscarine M1 acceptors and/or the spiro-compound of the activator of M4 acceptors | 赫普泰雅治疗有限公司 | 2017-11-28 | — | — | CN | claimed |
| CN-106458986-A | Bicyclic aza compounds as muscarinic M1 and/or M4 receptor agonists | 赫普泰雅治疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-118103352-A | Spiroindoline inhibitors of KIF18A | 沃拉斯查疗法公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117794918-A | Substituted tetrahydrofuran analogues as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-5463095-A | Process for the production of esters | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0629603-A1 | Process for the production of esters | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-3968133-A | Carboxylation process for preparing linear fatty acids or esters | TEXACO INC. (US) | 1976-07-06 | — | — | US | disclosed |