Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508291 | 0.94 | PPARD (0.42) | PPARDPPARA | |
| SCHEMBL3681587 | 0.94 | PPARD (0.42) | PPARDPPARA | |
| SCHEMBL3682941 | 0.81 | EPHX2 (0.35) | PPARD | |
| SCHEMBL13508352 | 0.75 | PPARD (0.45) | PPARD | |
| SCHEMBL3686617 | 0.75 | PPARD (0.45) | PPARD | |
| SCHEMBL13508351 | 0.74 | ALDH1A1 (0.47) | PPARD | |
| SCHEMBL3680749 | 0.74 | ALDH1A1 (0.47) | PPARD | |
| Trifluoroacetic Acid SCHEMBL3694964 | 0.71 | ESR1 (0.46) | PPARDPPARA | |
| SCHEMBL12093638 | 0.69 | ALDH1A1 (0.56) | PPARD | |
| SCHEMBL13508349 | 0.68 | PPARD (0.54) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | ELI LILLY AND COMPANY (US) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217433-A1 | Sulfonamide derivatives as ppar modulators | PPARD, PPARA, PPARG | PPARD 1/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.