Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686617 | 1.00 | PPARD (0.45) | PPARDSMN1; SMN2POLBALDH1A1TSHR | |
| SCHEMBL3690248 | 0.91 | PPARD (0.54) | PPARD | |
| SCHEMBL13508349 | 0.91 | PPARD (0.54) | PPARD | |
| SCHEMBL3683311 | 0.83 | PPARD (0.42) | PPARDALDH1A1ESR1GAANPSR1 | |
| SCHEMBL3683315 | 0.83 | PPARD (0.42) | PPARDALDH1A1ESR1GAANPSR1 | |
| SCHEMBL3680749 | 0.80 | ALDH1A1 (0.47) | PPARDALDH1A1 | |
| SCHEMBL13508351 | 0.80 | ALDH1A1 (0.47) | PPARDALDH1A1 | |
| SCHEMBL13508360 | 0.78 | LMNA (0.50) | PPARDSMN1; SMN2POLBALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL3682937 | 0.75 | PPARD (0.44) | PPARD | |
| SCHEMBL3681587 | 0.74 | PPARD (0.42) | PPARDSMN1; SMN2POLBALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |