SCHEMBL3045980

SCHEMBL3045980

O=C(O)[C@@H]1[C@@H]2CC[C@@H](C2)[C@@H]1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 6/20 0.46
TAAR1 Q96RJ0 2/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.43
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GMNN O75496 1/20 0.43
PMP22 Q01453 1/20 0.43
TFPI2 P48307 1/20 0.43
TP53 P04637 1/20 0.43
NFKB1 P19838 1/20 0.43
THPO P40225 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
MEN1 O00255 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14433686 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL19318992 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL3031493 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL7852169 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL23698034 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL187221 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL23176525 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL1004125 1.00 LMNA (0.52) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL407172 0.97 LMNA (0.50) LMNAKMT2AALDH1A1TAAR1MAPT
SCHEMBL31208131 0.97 LMNA (0.50) LMNAKMT2AALDH1A1TAAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163242-A1 POLYMERIC COMPOSITIONS CONTAINING A RANDOM COPOLYMER AND EFFECTS OF A GAMMA NUCLEATOR ON SUCH COMPOSITIONS FINA TECHNOLOGY, INC. 2025-05-22 US claimed
US-8207270-B2 blends of a propylene homo/copolymer, rubbers and crystallization agents, having superior crystallization kinetics, used as molding materials EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-06-26 US claimed
US-5117039-A Intermediates for Prostaglandin Preparation SHIONOGI & CO., LTD. (JP) 1992-05-26 US claimed
CN-116761706-B Thermoplastic polymer compositions and methods of making articles and films therefrom MILLIKEN & CO. (US) 2026-05-26 CN disclosed
US-12583984-B2 Thermoplastic polymer composition and method for making films from the same MILLIKEN & COMPANY (US) 2026-03-24 US disclosed
US-20250163242-A1 POLYMERIC COMPOSITIONS CONTAINING A RANDOM COPOLYMER AND EFFECTS OF A GAMMA NUCLEATOR ON SUCH COMPOSITIONS FINA TECHNOLOGY, INC. 2025-05-22 US disclosed
EP-4284622-B1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR MAKING ARTICLES AND FILMS FROM THE SAME MILLIKEN & CO (US) 2025-04-30 EP disclosed
EP-4188672-B1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR MAKING FILMS FROM THE SAME MILLIKEN & CO (US) 2025-04-02 EP disclosed
EP-4189009-B1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR MOLDING THE SAME MILLIKEN & CO (US) 2025-03-26 EP disclosed
CN-116157248-B Thermoplastic polymer composition and molding method thereof 美利肯公司 2025-01-07 CN disclosed
US-20240400774-A1 THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR MAKING FILMS FROM THE SAME MILLIKEN & COMPANY 2024-12-05 US disclosed
US-20080269344-A1 Beta2-Adrenergic Receptor Agonists THERAVANCE BIOPHARMA R&D IP, LLC 2008-10-30 US disclosed
US-20060155073-A1 Polypropylene resin composition and formed article SUMITOMO CHEMICAL COMPANY, LIMITED 2006-07-13 US disclosed
US-5241104-A Reacting acid anhydride with arylacetic acid derivatives; for preparing optically active prostaglandins SHIONOGI & CO., LTD. (JP) 1993-08-31 US disclosed
EP-0373949-B1 MONO ESTERS OF DICARBOXYLIC ACIDS, THEIR PREPARATION AND USE SHIONOGI & CO (JP) 1993-08-25 EP disclosed
US-5233011-A Melt extruding polyimide, moisture control; heat resistance MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-08-03 US disclosed
US-5183909-A Useful as intermediate for production of prostaglandins, terpenes, aminosugars, nucleotides and alkaloids SHIONOGI & COMPANY, LTD. (JP) 1993-02-02 US disclosed
US-5175341-A Bicyclo 2.2.2!heptanedicarboxylic acid derivatives SHIONOGI & CO., LTD. (JP) 1992-12-29 US disclosed
US-5047574-A CHEMICAL INTERMEDIATES FOR OPTICALLY ACTIVE PRODUCTS, MEDICINES SHIONOGI & CO., LTD. (JP) 1991-09-10 US disclosed
EP-0373949-A1 Mono esters of dicarboxylic acids, their preparation and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583984-B2 Thermoplastic polymer composition and method for making films from the same TAF1, PARG, MDC1 LMNA 482/4885KMT2A 2582/4885ALDH1A1 4010/4885
US-20080269344-A1 Beta2-Adrenergic Receptor Agonists ADRB2, ADRB1, ADRA2B LMNA 617/4885KMT2A 4173/4885ALDH1A1 1061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.