SCHEMBL4320539

SCHEMBL4320539

CCOC(=O)c1ccccc1-c1ccccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.67
CA12 O43570 3/20 0.58
CA1 P00915 3/20 0.58
CA2 P00918 3/20 0.58
CA7 P43166 3/20 0.58
CA9 Q16790 3/20 0.58
CA14 Q9ULX7 3/20 0.58
ALDH1A1 P00352 3/20 0.57
HSD17B10 Q99714 1/20 0.57
KDM4E B2RXH2 1/20 0.57
CDC25B P30305 2/20 0.54
MEN1 O00255 1/20 0.52
USP2 O75604 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP2C19 P33261 1/20 0.52
MAPK10 P53779 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683272 0.91 TSHR (0.80) TSHRCA12CA1CA2CA7
SCHEMBL29617021 0.91 TSHR (0.80) TSHRCA12CA1CA2CA7
SCHEMBL27570718 0.86 ALDH1A1 (0.58) TSHRCA12CA1CA2CA7
Ethyl Salicylate SCHEMBL29501114 0.85 TSHR (0.77) TSHRCA12CA1CA2CA7
Ethyl Salicylate SCHEMBL39622 0.85 TSHR (0.77) TSHRCA12CA1CA2CA7
Ethyl Salicylate SCHEMBL1870434 0.85 TSHR (0.77) TSHRCA12CA1CA2CA7
SCHEMBL5572323 0.84 TSHR (0.69) TSHRALDH1A1HSD17B10KDM4ECDC25B
SCHEMBL8075091 0.84 TSHR (0.69) TSHRALDH1A1HSD17B10KDM4ECDC25B
SCHEMBL3950053 0.84 TSHR (0.69) TSHRALDH1A1HSD17B10KDM4ECDC25B
Ethyl Salicylate SCHEMBL23045199 0.84 TSHR (0.74) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527837-B2 Composition containing a polymerizable optically active compound CHISSO CORPORATION (JP) 2009-05-05 US disclosed
US-20070122565-A1 1-15% 1,1'-Binaphthyl-2,2'-diol diesterified with 3-alkyl-3-oxetanylmethoxyaryl-carboxylic acid, -propionic acid or -acrylic acid; 5-45% arylenediol diesterified with p-(3-alkyl-3-oxetanylmethoxyalkoxy)benzoic acid; and 45-80% p-(epoxyalkoxy)phenyl p-(epoxyalkoxy)benzoate; optical anisotropy JNC PETROCHEMICAL CORPORATION (JP) 2007-05-31 US disclosed