SCHEMBL3683289

SCHEMBL3683289

C=C(CCC(=O)CC(C)=O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.60
KDM6B O15054 1/20 0.60
KDM5C P41229 1/20 0.60
EGLN1 Q9GZT9 1/20 0.60
PHF8 Q9UPP1 1/20 0.60
KDM2A Q9Y2K7 1/20 0.60
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TET2 Q6N021 4/20 0.34
LMNA P02545 2/20 0.33
SLC15A2 Q16348 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HAO1 Q9UJM8 1/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
GRIK1 P39086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1224391 0.87 KDM4E (0.50) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL3682486 0.81 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL474841 0.80 ALDH1A1 (0.56) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL61062 0.80 KDM4E (0.78) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL11608071 0.78 KDM4E (0.61) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL6656723 0.78
SCHEMBL273086 0.77 TET2 (0.46) EGLN1ALOX15HSD17B10TET2LMNA
SCHEMBL8620250 0.76 TDP1 (0.43) KDM4EKDM6BKDM5CEGLN1PHF8
Succinylacetone SCHEMBL503918 0.75 PHF8 (1.00) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL517189 0.75 TET2 (0.39) ALOX15HSD17B10TET2LMNASLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2180785-A2 USE OF HOMO- AND COPOLYMERS FOR STABILIZING ACTIVE INGREDIENT FORMULATIONS BASF SE (DE) 2010-05-05 EP disclosed
WO-2009007328-A2 USE OF HOMO- AND COPOLYMERS FOR STABILIZING ACTIVE INGREDIENT FORMULATIONS BASF SE (DE) 2009-01-15 WO disclosed
EP-1144474-B1 AQUEOUS REACTIVE PUTTY (I) BAYER AG (DE) 2003-09-10 EP disclosed
EP-1144474-A1 AQUEOUS REACTIVE PUTTY (I) Bayer Aktiengesellschaft (DE) 2001-10-17 EP disclosed
WO-2000037523-A1 AQUEOUS REACTIVE PUTTY (I) BAYER AKTIENGESELLSCHAFT (DE) 2000-06-29 WO disclosed
EP-0034788-B1 EMULSION LACQUER AND PROCESS FOR PRODUCING PLANOGRAPHIC PRINTING FORMES HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-13 EP disclosed