SCHEMBL61062

SCHEMBL61062

CC(=O)CC(=O)CCC(=O)CC(C)=O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.78
KDM5C P41229 2/20 0.78
EGLN1 Q9GZT9 2/20 0.78
PHF8 Q9UPP1 2/20 0.78
KDM2A Q9Y2K7 2/20 0.78
KDM6B O15054 1/20 0.78
ALDH1A1 P00352 4/20 0.50
MGAM O43451 1/20 0.45
GAA P10253 1/20 0.45
SI P14410 1/20 0.45
MGAM2 Q2M2H8 1/20 0.45
TDP1 Q9NUW8 3/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 3/20 0.40
SLC15A2 Q16348 1/20 0.40
TRPA1 O75762 1/20 0.39
GABRR1 P24046 1/20 0.36
TSHR P16473 1/20 0.35
ACHE P22303 1/20 0.33
PAOX Q6QHF9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7016070 0.94 KDM4E (0.70) KDM4EKDM5CEGLN1PHF8KDM2A
Succinylacetone SCHEMBL503918 0.88 PHF8 (1.00) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL8846311 0.87 KDM4E (0.62) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL11608071 0.86 KDM4E (0.61) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL19582818 0.86 KDM4E (0.61) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL20599060 0.86 KDM4E (0.61) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL235434 0.85 KDM4E (0.58) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL10958948 0.84 KDM4E (0.59) KDM4EKDM5CEGLN1PHF8KDM2A
SCHEMBL516260 0.84
SCHEMBL11247778 0.84 KDM4E (0.59) KDM4EKDM5CEGLN1PHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2197829-B1 ARYLAMINE SYNTHESIS METHOD CENTRE NAT RECH SCIENT (FR) 2016-05-04 EP claimed
US-20120085371-A1 METHOD AND COMPOSITION FOR CLEANING OBJECTS BUBBLES AND BEYOND GMBH (DE) 2012-04-12 US claimed
EP-2376376-A2 PHOSPHATE BASED COMPOUND, USE OF THE COMPOUND IN AN ELECTROCHEMICAL STORAGE DEVICE AND METHODS FOR ITS PREPARATION Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2011-10-19 EP claimed
US-20080191161-A1 Ink for Producing Catalyst Layers UMICORE AG & CO. KG (DE) 2008-08-14 US claimed
US-6462246-B2 ALKENYLATING AN AROMATIC HYDROCARBON WITH AN OLEFIN IN THE PRESENCE OF BETA-DIKETONE AND RHODIUM COMPLEX CATALYST; WITHOUT USE OF CARBOXYLIC ACID SUCH AS ACETIC ACID NIPPON MITSUBISHI OIL CORPORATION (JP) 2002-10-08 US claimed
US-20010037044-A1 Method of preparing alkenyl-substituted aromatic hydrocarbon NIPPON MITSUBISHI OIL CORPORATION 2001-11-01 US claimed
JP-54046299-A None JP disclosed
US-10725376-B2 Pattern-forming method JSR CORPORATION (JP) 2020-07-28 US disclosed
US-20170184961-A1 PATTERN-FORMING METHOD JSR CORPORATION (JP) 2017-06-29 US disclosed
US-20120270139-A1 CATHODE MATERIAL FOR A FUEL CELL, CATHODE INCLUDING THE CATHODE MATERIAL, AND A SOLID OXIDE FUEL CELL INCLUDING THE CATHODE MATERIAL SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-25 US disclosed
US-8026374-B2 Process for preparing (meth)acrylic esters of N-hydroxyalkylated imidazoles BASF SE (DE) 2011-09-27 US disclosed
EP-1577282-B1 Metal complexes for use in olefin metathesis and atom or group transfer reactions TELENE SAS (FR) 2011-06-15 EP disclosed
US-7906452-B2 high storage stability; for producing catalyst-coated substrates for electrochemical devices, in particular fuel cells; stable to oxidative degradation UMICORE AG & CO. KG (DE) 2011-03-15 US disclosed
US-5059731-A Selectively hydrogenating acetylenic and diolefinic hydrocarbons EUROPEANE DE RETRAITEMENT DE CATALYSEURS EURECAT (FR) 1991-10-22 US disclosed
US-5032565-A Using aldehyde, ketone, alcohol, ether or acid EUROPEENNE RETRAITEMENT DE CATALYSEURS EURECAT (FR) 1991-07-16 US disclosed
US-4457978-A AIR POLLUTION CONTROL; WEAK ACID, CALCIUM METASILICATE WAWZONEK STANLEY 1984-07-03 US disclosed
JP-S5446299-A CURABLE EPOXY RESIN COMPOSITION MITSUBISHI ELECTRIC CORP 1979-04-12 JP disclosed
US-4116869-A POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1978-09-26 US disclosed
US-4095017-A VINYL MONOMER POLYMERIZATION OR COPOLYMERIZATION CATALYZED BY ORGANOALUMINUM-ORGANOPHOSPHINE-METAL SALT OF A BETA-DIKETONE CATALYST SYSTEM PHILLIPS PETROLEUM COMPANY (US) 1978-06-13 US disclosed
US-4020018-A Alkene oxide or acrylate polymerization or copolymerization catalyzed by organoaluminum-organophosphine-metal salt of a beta-diketone PHILLIPS PETROLEUM COMPANY (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037044-A1 Method of preparing alkenyl-substituted aromatic hydrocarbon AHR, ARNT, ALKBH3 KDM4E 753/4885KDM5C 421/4885EGLN1 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.