SCHEMBL3683341

SCHEMBL3683341

COC(=O)[C@@H]1[C@@H](C=C(C)C)C1(C)C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.66
TSHR P16473 4/20 0.49
CYP1A2 P05177 3/20 0.49
CYP2C19 P33261 3/20 0.49
TDP1 Q9NUW8 3/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
ALOX15 P16050 1/20 0.39
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
ADRA2A P08913 1/20 0.32
CNR1 P21554 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2219671 1.00 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL294747 1.00 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL6439369 1.00 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10989214 1.00 LMNA (0.66) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10955859 0.87 LMNA (0.56) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10978738 0.86 LMNA (0.68) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10598336 0.86 LMNA (0.68) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL10598328 0.86 LMNA (0.68) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL9718715 0.86 LMNA (0.68) LMNATSHRCYP1A2CYP2C19TDP1
SCHEMBL7639324 0.85 LMNA (0.49) LMNATSHRCYP1A2CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9247750-B2 Polyenylcyclopropanecarboxylic esters with high insecticidal activity ENDURA S.P.A. (IT) 2016-02-02 US disclosed
US-20100210721-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY ENDURA S.P.A. (IT) 2010-08-19 US disclosed
EP-1203760-B1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2005-04-13 EP disclosed
US-6706910-B2 BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-16 US disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052525-A1 Method for producing cyclopropanecarboxylates CYP8B1, SRD5A2, CYP21A2 LMNA 1815/4885TSHR 1601/4885CYP1A2 39/4885
US-20100210721-A1 POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY DDT, MCCC2, PCCA LMNA 1338/4885TSHR 4210/4885CYP1A2 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.