SCHEMBL3683889

SCHEMBL3683889

C=CC(=O)N[SiH2]OC(C)(C)CCC

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27747780 0.74 ZDHHC20 (0.38) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1108010 0.67 TSHR (0.44) ALDH1A1TSHRMAPK1CYP3A4HPGD
SCHEMBL4906709 0.67 KMT2A (0.53) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL9398270 0.67 ALDH1A1 (0.42) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL4279871 0.66
SCHEMBL21728862 0.65 ZDHHC20 (0.44) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL1155743 0.65
SCHEMBL8764635 0.65 ALDH1A1 (0.40) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1
SCHEMBL5361003 0.64
Hydrochloric Acid SCHEMBL21990280 0.63 ALDH1A1 (0.39) ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384485-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS Wacker Chemie AG (DE) 2024-06-19 EP disclosed
WO-2023016627-A1 CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS WACKER CHEMIE AG (DE) 2023-02-16 WO disclosed
EP-2252650-B1 COLLOIDAL AQUEOUS ORGANOPOLYSILOXANE DISPERSIONS WHICH CONTAIN BINDERS AND THE USE THEREOF WACKER CHEMIE AG (DE) 2011-12-28 EP disclosed
EP-2252650-A1 COLLOIDAL AQUEOUS ORGANOPOLYSILOXANE DISPERSIONS WHICH CONTAIN BINDERS AND THE USE THEREOF Wacker Chemie AG (DE) 2010-11-24 EP disclosed
WO-2009112394-A1 COLLOIDAL AQUEOUS ORGANOPOLYSILOXANE DISPERSIONS WHICH CONTAIN BINDERS AND THE USE THEREOF WACKER CHEMIE AG (DE) 2009-09-17 WO disclosed
EP-1549682-A1 POLYMERS CONTAINING SILANE Wacker Polymer Systems GmbH & Co. KG (DE) 2005-07-06 EP disclosed
WO-2004013187-A1 POLYMERS CONTAINING SILANE WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2004-02-12 WO disclosed