Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 14/20 | 0.57 |
| ▸ | PGR | P06401 | 13/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653908 | 0.82 | NR3C1 (0.55) | NR3C1NR3C2PGR | |
| SCHEMBL3684073 | 0.81 | NR3C1 (0.42) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634355 | 0.79 | NR3C1 (0.67) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1635102 | 0.78 | NR3C1 (0.71) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1635345 | 0.77 | NR3C1 (0.70) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634433 | 0.75 | NR3C1 (0.77) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1633555 | 0.75 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1635848 | 0.75 | NR3C1 (0.77) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL4037364 | 0.75 | NR3C1 (0.42) | NR3C1NR3C2PGRDAODDO | |
| SCHEMBL14340577 | 0.74 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061444-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | Bausch & Lomb Incorporated (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-2051710-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | Bausch & Lomb Incorporated (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008033655-A2 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB INCORPORATED (US) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008021729-A2 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |