SCHEMBL3684155

SCHEMBL3684155

O=C1c2ccc(Cl)c(Cl)c2C(=O)N1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.37
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
AHR P35869 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
ERCC1 P07992 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
FEN1 P39748 1/20 0.33
ERCC4 Q92889 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650190 0.78 POLB (0.51) CES1HTR2AHTR2CHTR2BKDM4E
SCHEMBL458385 0.75 CYP3A4 (0.35) ALDH1A1AHR
SCHEMBL454552 0.75 KDM4E (0.41) CES1KDM4EALDH1A1KMT2APOLB
Ethylene SCHEMBL16860553 0.72 CYP3A4 (0.32) ALDH1A1AHR
SCHEMBL10732300 0.70 MEN1 (0.60) CES1KDM4EALDH1A1AHRKMT2A
SCHEMBL9210551 0.70 HEXA (0.47) KDM4EALDH1A1LMNA
SCHEMBL9438317 0.68 CA1 (0.53) KMT2AMEN1LMNA
SCHEMBL8407062 0.67 DNMT1 (0.50) CES1KDM4EALDH1A1KMT2APOLB
SCHEMBL11214758 0.67 HSPA1A (0.55) HTR2BKDM4EALDH1A1KMT2APOLB
SCHEMBL11716012 0.67 KDM4E (0.35) KDM4EALDH1A1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525066-B1 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID OCCIDENTAL CHEM CO (US) 1997-06-18 EP claimed
US-5596104-A Preparation of 3,4,6-trifluorophthalic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1997-01-21 US claimed
EP-0525066-A4 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID 1993-03-17 EP claimed
EP-0525066-A1 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID. OCCIDENTAL CHEM CO (US) 1993-02-03 EP claimed
WO-1991016308-A1 PREPARATION OF 3,4,6-TRIFLUOROPHTHALIC ACID OCCIDENTAL CHEMICAL CORPORATION (US) 1991-10-31 WO claimed
EP-2152803-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION Sabic Innovative Plastics IP B.V. (NL) 2010-02-17 EP disclosed
WO-2008149260-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSITION SABIC INNOVATIVE PLASTICS IP B.V. (US) 2008-12-11 WO disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
US-6187931-B1 Process for making fluorophthalimides ALBEMARLE CORPORATION 2001-02-13 US disclosed
US-5668201-A Flame retardant graft copolymer composition GENERAL ELECTRIC COMPANY (US) 1997-09-16 US disclosed
EP-0563986-B1 Process for selective hydrodefluorination OCCIDENTAL CHEM CO (US) 1997-09-03 EP disclosed
EP-0475781-B1 Aquatic antifouling compositions ROHM & HAAS (US) 1995-12-13 EP disclosed
EP-0495426-A2 Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-07-22 EP disclosed
EP-0495426-A2 Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-07-22 EP disclosed
EP-0485213-A1 Aquatic antifouling compositions ROHM AND HAAS COMPANY (US) 1992-05-13 EP disclosed
EP-0475781-A1 Aquatic antifouling compositions ROHM AND HAAS COMPANY (US) 1992-03-18 EP disclosed
US-5086188-A Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-02-04 US disclosed
US-5086188-A Preparation of 3,5-dichlorophthalic acid and 3,5-dichlorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-02-04 US disclosed
EP-0219014-A2 Flame retardant elastomeric compositions GENERAL ELECTRIC COMPANY (US) 1987-04-22 EP disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed