SCHEMBL3684342

SCHEMBL3684342

Cc1c(Cl)ccc(O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 4/20 0.39
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 2/20 0.39
TRPA1 O75762 2/20 0.39
SHBG P04278 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
PIK3CA P42336 1/20 0.35
PIM1 P11309 1/20 0.35
ADAMTS4 O75173 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699414 0.83 DPP4 (0.42) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL335595 0.81 CYP3A4 (0.48) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL29566553 0.81 CYP3A4 (0.48) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
Water SCHEMBL29243256 0.79 CYP3A4 (0.46) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL3246842 0.79 CYP3A4 (0.59) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL48082 0.79 ALDH1A1 (0.43) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL3790032 0.79 CYP3A4 (0.46) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL3034116 0.79 CES1 (0.41) CYP3A4MAPK1HSD17B10ALDH1A1TDP1
SCHEMBL3708636 0.77 TRPA1 (0.46) MAPK1HSD17B10ALDH1A1TDP1TRPA1
SCHEMBL31290749 0.77 TRPA1 (0.46) MAPK1HSD17B10ALDH1A1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101070198-A Method for thoroughly degradating chloroguaiacol pulp bleaching waste-water GUANGXI NATIONNALITY UNIV (CN) 2007-11-14 CN claimed
WO-2020132603-A2 SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2020-06-25 WO disclosed
US-7820862-B2 Ligand, method for producing the same, and catalyst using the ligand THE UNIVERSITY OF TOKYO (JP) 2010-10-26 US disclosed
US-20090023579-A1 Ligand, Method for Producing the Same, and Catalyst Using the Ligand THE UNIVERSITY OF TOKYO (JP) 2009-01-22 US disclosed
EP-1995250-A1 LIGAND, METHOD FOR PRODUCING THE SAME, AND CATALYST USING THE LIGAND The University of Tokyo (JP) 2008-11-26 EP disclosed
CN-101070198-A Method for thoroughly degradating chloroguaiacol pulp bleaching waste-water GUANGXI NATIONNALITY UNIV (CN) 2007-11-14 CN disclosed
US-6759435-B1 SUCH AS METHYL-(1-(2-(1-PHENYL-ETHYL)-PHENYL)-ETHYL)-AMINE; SEROTONIN REUPTAKE INHIBITORS A.P. Group Inc. 2004-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023579-A1 Ligand, Method for Producing the Same, and Catalyst Using the Ligand CHRM1, CHRM2, B3GNT2 CYP3A4 431/4885MAPK1 3186/4885HSD17B10 1982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.