Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681221 | 1.00 | CYP1A2 (0.47) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL3686039 | 0.92 | CYP1A2 (0.51) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL3683915 | 0.92 | CYP1A2 (0.51) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL29949905 | 0.92 | CYP1A2 (0.51) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL1655376 | 0.90 | CYP1A2 (0.52) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL3687052 | 0.88 | ALDH1A1 (0.50) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL17940742 | 0.87 | HDAC8 (0.45) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL16792034 | 0.84 | CA12 (0.53) | CYP1A2CA12CA1CA2CA9 | |
| SCHEMBL2293036 | 0.84 | ALDH1A1 (0.43) | CYP1A2ALDH1A1THRBHPGDHSD17B10 | |
| SCHEMBL2292638 | 0.84 | ALDH1A1 (0.43) | CYP1A2ALDH1A1THRBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103709180-B | Containing the condensed-nuclei aromatics derivant of imidazo [1,2-a] pyridine groups and the application in OLED thereof | 昆山维信诺显示技术有限公司 | 2016-12-21 | — | — | CN | disclosed |
| CN-103709180-A | Polycyclic aromatic hydrocarbon derivatives containing imidazoxy [1,2, a] pyridyl group and their use in OLED | KUNSHAN VISIONOX DISPLAY TECH | 2014-04-09 | — | — | CN | disclosed |
| US-8318995-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-7763761-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1749809-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| US-20060154107-A1 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | ESR1, EBPL, JUP | CYP1A2 169/4885CA12 3619/4885CA1 3383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.