Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TYK2 | P29597 | 1/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519361 | 1.00 | HPGD (0.79) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7058035 | 0.90 | RAB9A (0.79) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL21993 | 0.89 | HPGD (1.00) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11781486 | 0.87 | HPGD (0.77) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL3468940 | 0.86 | HPGD (0.74) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL5038860 | 0.86 | HPGD (0.74) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL14688750 | 0.86 | NPC1 (0.63) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL2119568 | 0.86 | HPGD (0.74) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL19501494 | 0.86 | HPGD (0.86) | HPGDSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL679010 | 0.86 | HPGD (0.74) | HPGDSMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62018289-A | — | — | None | — | — | JP | disclosed |
| US-12497712-B2 | Property modulation with chemical transformations | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2025-07-24 | — | — | US | disclosed |
| WO-2023061440-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-04-20 | — | — | WO | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| US-20200370204-A1 | PROPERTY MODULATION WITH CHEMICAL TRANSFORMATIONS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-11-26 | — | — | US | disclosed |
| CN-104193750-B | Suppress mitotic Compounds and methods for by suppressing aurora kinase | 千禧药品公司 | 2018-04-27 | — | — | CN | disclosed |
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-8647528-B2 | Water absorbing agent and production method thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| WO-2012129562-A2 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-27 | — | — | WO | disclosed |
| US-20080070124-A1 | COMPOSITION FOR HOLOGRAPHIC RECORDING MEDIUM, HOLOGRAPHIC RECORDING MEDIUM, AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2008-03-20 | — | — | US | disclosed |
| CN-1287046-C | Method for producing paper and yield-improving agent | SEIKO PMC CORP (JP) | 2006-11-29 | — | — | CN | disclosed |
| EP-1682181-A2 | COMBINATION OF A VEGF RECEPTOR INHIBITOR WITH A CHEMOTHERAPEUTIC AGENT | Novartis AG (CH) | 2006-07-26 | — | — | EP | disclosed |
| CN-1643215-A | Method for producing paper and yield-improving agent | SEIKO PMC CORP (JP) | 2005-07-20 | — | — | CN | disclosed |
| WO-2005027972-A2 | COMBINATION OF A VEGF RECEPTOR INHIBITOR WITH A CHEMOTHERAPEUTIC AGENT | NOVARTIS AG (CH) | 2005-03-31 | — | — | WO | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |
| EP-1129075-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | Novartis AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027820-A1 | N-ARYL(THIO)ANTHRANILIC ACID AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS VEGF RECEPTOR TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | disclosed |
| JP-S6218289-A | THERMAL RECORDING MATERIAL | MITSUI TOATSU CHEM INC | 1987-01-27 | — | — | JP | disclosed |
| US-4123554-A | Fungicidal and germicidal benzanilides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, TP53BP1 | HPGD 3546/4885SMN1; SMN2 2871/4885NPC1 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.