Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.79 |
| ▸ | NPC1 | O15118 | 7/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 2/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.79 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.79 |
| ▸ | RELA | Q04206 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | PNLIP | P16233 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489953 | 0.93 | ALDH1A1 (0.76) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL5742618 | 0.91 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL3684485 | 0.90 | HPGD (0.79) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL29519361 | 0.90 | HPGD (0.79) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL5079177 | 0.89 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL13475431 | 0.88 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL8060238 | 0.87 | NPC1 (0.75) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL1961876 | 0.87 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL11590379 | 0.87 | KMT2A (0.74) | RAB9ANPC1SMN1; SMN2LMNATP53 | |
| SCHEMBL8055108 | 0.87 | SMO (0.71) | RAB9ANPC1SMN1; SMN2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263861-B1 | RUBBER VULCANIZATES HAVING IMPROVED AGEING PROPERTIES | FLEXSYS BV (NL) | 2004-01-28 | — | — | EP | disclosed |
| EP-1263861-A1 | RUBBER VULCANIZATES HAVING IMPROVED AGEING PROPERTIES | Flexsys B.V. (NL) | 2002-12-11 | — | — | EP | disclosed |
| US-6444759-B2 | CONTAINING N,N'-DISUBSTITUTED PHENYLENEDIAMINE COMPOUND | FLEXSYS B.V. (NL) | 2002-09-03 | — | — | US | disclosed |
| US-20010031836-A1 | Rubber vulcanizates having improved ageing properties | FLEXSYS B.V. (NL) | 2001-10-18 | — | — | US | disclosed |
| WO-2001068761-A1 | RUBBER VULCANIZATES HAVING IMPROVED AGEING PROPERTIES | FLEXSYS B.V. (NL) | 2001-09-20 | — | — | WO | disclosed |