Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938342 | 0.85 | TDP1 (0.37) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8669663 | 0.81 | ALDH1A1 (0.38) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11774105 | 0.80 | ALDH1A1 (0.51) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL9723920 | 0.80 | ALDH1A1 (0.54) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11237291 | 0.79 | HTT (0.39) | TSHRTDP1L3MBTL1MAPK1TP53 | |
| 1,4-Butanediol SCHEMBL10355199 | 0.78 | TSHR (0.59) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL10790805 | 0.78 | TSHR (0.55) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL5083435 | 0.78 | TDP1 (0.40) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| Phthalic Acid SCHEMBL28828777 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4EMEN1RECQL | |
| Phthalic Acid SCHEMBL28341019 | 0.78 | TDP1 (0.49) | TSHRTDP1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249291-A1 | REACTIVE HOT-MELT COMPOSITION AND MOLDED ARTICLE USING THE SAME | UBE INDUSTRIES, LTD. (JP) | 2010-09-30 | — | — | US | disclosed |