Dimethylamine

Dimethylamine

SCHEMBL3684568

CCC(=O)Cc1ccccc1.CNC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
AKR1B1 P15121 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
EPHX2 P34913 1/20 0.47
POLB P06746 1/20 0.46
CNR2 P34972 1/20 0.45
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HSD11B1 P28845 1/20 0.44
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27614820 0.94 CES1 (0.58) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL43241 0.94 CES1 (0.58) CES1CES2AKR1B1MEN1KMT2A
Water SCHEMBL27427566 0.91 CES1 (0.56) CES1CES2AKR1B1MEN1KMT2A
Benzene SCHEMBL27747096 0.91 CES1 (0.56) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL10999568 0.91 CES1 (0.56) CES1CES2AKR1B1MEN1KMT2A
Methane SCHEMBL2442457 0.91 CES1 (0.56) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL29897949 0.90 LMNA (0.55) CES1CES2AKR1B1MEN1KMT2A
Butane SCHEMBL11691843 0.89 CES1 (0.54) CES1CES2AKR1B1MEN1KMT2A
Urea SCHEMBL6171504 0.88 CES1 (0.52) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL7503862 0.88 CES2 (0.52) CES1CES2AKR1B1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1332162-B1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS BRIDGESTONE CORP (JP) 2013-05-01 EP claimed
US-7642322-B2 such as 4,4'-bis(N,N-dimethylamino)benzophenone, 4,4'-bis(N,N-diethylamino)benzophenone; living polymers; lanthanide-based polymerization catalysts BRIDGESTONE CORPORATION (JP) 2010-01-05 US claimed
US-20060004131-A1 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents OZAWA YOICHI 2006-01-05 US claimed
US-9644052-B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents BRIDGESTONE CORPORATION (JP) 2017-05-09 US disclosed
US-20150259452-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS JSR CORPORATION (JP) 2015-09-17 US disclosed
US-8987362-B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents BRIDGESTONE CORP (JP) 2015-03-24 US disclosed
US-20140100339-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS JSR CORPORATION (JP) 2014-04-10 US disclosed
US-8618199-B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents OZAWA YOICHI F (JP) 2013-12-31 US disclosed
EP-1332162-B1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS BRIDGESTONE CORP (JP) 2013-05-01 EP disclosed
US-20130102736-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS OZAWA YOICHI (JP) 2013-04-25 US disclosed
US-8362126-B2 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents OZAWA YOICHI (JP) 2013-01-29 US disclosed
US-20100099826-A1 FUNTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS OZAWA YOICHI 2010-04-22 US disclosed
US-7642322-B2 such as 4,4'-bis(N,N-dimethylamino)benzophenone, 4,4'-bis(N,N-diethylamino)benzophenone; living polymers; lanthanide-based polymerization catalysts BRIDGESTONE CORPORATION (JP) 2010-01-05 US disclosed
US-20060004131-A1 Functionalized high cis-1,4-polybutadiene prepared using novel functionalizing agents OZAWA YOICHI 2006-01-05 US disclosed
EP-1332162-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS Bridgestone Corporation (JP) 2003-08-06 EP disclosed
WO-2002038615-A1 FUNCTIONALIZED HIGH CIS-1,4-POLYBUTADIENE PREPARED USING NOVEL FUNCTIONALIZING AGENTS BRIDGESTONE CORPORATION (JP) 2002-05-16 WO disclosed