Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.49 |
| ▸ | PGR | P06401 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291220 | 0.88 | NR3C1 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL1634911 | 0.81 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL6908248 | 0.80 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL27774891 | 0.78 | NR3C1 (0.41) | NR3C1NR3C2PGR | |
| SCHEMBL15103449 | 0.78 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL3651952 | 0.77 | NR3C1 (0.48) | NR3C1NR3C2PGR | |
| SCHEMBL6916338 | 0.77 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL3654089 | 0.77 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL1634887 | 0.76 | NR3C1 (0.73) | NR3C1NR3C2PGR | |
| SCHEMBL292721 | 0.75 | NR3C1 (0.66) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |